Parameter | Value |
---|---|
Gene | Hist1h2ai |
Protein Name | H2A1I_MOUSE |
Organism | Mus musculus (Mouse) |
Alternative name(s) | Histone H2A type 1-I |
Protein Family | Histone H2A family |
NCBI Gene ID | 3.19E+53 |
UniProt ID | C0HKE6 |
Enzyme Class | - |
Molecular Weight | 14135 |
Protein Length | 130 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Nucleus. Chromosome. |
Function (UniProt annotation) | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Gene Ontology | GO:0000786; GO:0003677; GO:0005634; GO:0008285; GO:0046982 |
No Kinases found
Reactome Pathways
KEGG Pathways
Pathway ID | Pathway Name |
---|---|
mmu05322 | Systemic lupus erythematosus |
No NCI Nature pathways found