| Parameter | Value |
|---|---|
| Gene | Hist1h2ap |
| Protein Name | H2A1P_MOUSE |
| Organism | Mus musculus (Mouse) |
| Alternative name(s) | Histone H2A type 1-P |
| Protein Family | Histone H2A family |
| NCBI Gene ID | 3.19E+53 |
| UniProt ID | C0HKE9 |
| Enzyme Class | - |
| Molecular Weight | 14135 |
| Protein Length | 130 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Nucleus. Chromosome. |
| Function (UniProt annotation) | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Gene Ontology | GO:0000786; GO:0003677; GO:0005634; GO:0046982 |
No Kinases found
Reactome Pathways
KEGG Pathways
| Pathway ID | Pathway Name |
|---|---|
| mmu05322 | Systemic lupus erythematosus |
No NCI Nature pathways found