| Gene |
KCNK3
|
| Protein Name |
KCNK3_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1) (Two pore K(+) channel KT3.1) |
| Protein Family |
Two pore domain potassium channel (TC 1.A.1.8) family |
| NCBI Gene ID |
3777
|
| UniProt ID |
O14649
|
| Enzyme Class |
- |
| Molecular Weight |
43518 |
| Protein Length |
394 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cell membrane |
| Function (UniProt annotation) |
pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward. |
| Gene Ontology |
GO:0005216; GO:0005252; GO:0005267; GO:0005615; GO:0005886; GO:0005887; GO:0006813; GO:0007268; GO:0007420; GO:0008022; GO:0008083; GO:0022841; GO:0034220; GO:0042493; GO:0044548; GO:0051481; GO:0061337; GO:0071294; GO:0071456; GO:0071805; GO:0090102 |
