Graphics credits: COMPARTMENTS | More Info
Parameter | Value |
---|---|
Gene | FANCA |
Protein Name | FANCA_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | Fanconi anemia group A protein (Protein FACA) |
Protein Family | N/A |
NCBI Gene ID | 2175 |
UniProt ID | O15360 |
Enzyme Class | - |
Molecular Weight | 162775 |
Protein Length | 1455 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic. |
Function (UniProt annotation) | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. |
Gene Ontology | GO:0005634; GO:0005654; GO:0005737; GO:0006281; GO:0007140; GO:0008584; GO:0008585; GO:0036297; GO:0042127; GO:0043240; GO:0045589; GO:0050727; GO:0051090; GO:0065003; GO:2000348 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
PRKAA1 (Q13131) | Homo sapiens | S347 | VQMQREWSFARTHPL | 0.688 | 0.1969 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found