| Gene |
MYC
|
| Protein Name |
MYC_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64) |
| Protein Family |
N/A |
| NCBI Gene ID |
4609
|
| UniProt ID |
P01106
|
| Enzyme Class |
- |
| Molecular Weight |
48804 |
| Protein Length |
439 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Nucleus, nucleoplasm |
| Function (UniProt annotation) |
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000). |
| Gene Ontology |
GO:0000082; GO:0000122; GO:0000165; GO:0000790; GO:0000978; GO:0000981; GO:0001077; GO:0001227; GO:0001658; GO:0002053; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005730; GO:0006112; GO:0006338; GO:0006357; GO:0006879; GO:0006974; GO:0007050; GO:0007219; GO:0008134; GO:0008284; GO:0010332; GO:0010468; GO:0010628; GO:0015671; GO:0016579; GO:0019221; GO:0032204; GO:0032873; GO:0032986; GO:0032991; GO:0033613; GO:0034644; GO:0035690; GO:0042493; GO:0043066; GO:0043280; GO:0044346; GO:0044877; GO:0045656; GO:0045893; GO:0045944; GO:0046983; GO:0048146; GO:0048147; GO:0050679; GO:0051276; GO:0051782; GO:0051973; GO:0070371; GO:0070491; GO:0070848; GO:0070888; GO:0071456; GO:0090096; GO:1904837; GO:1905643; GO:2000573; GO:2001022 |
