| Gene |
CRYAB
|
| Protein Name |
CRYAB_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component) |
| Protein Family |
Small heat shock protein (HSP20) family |
| NCBI Gene ID |
1410
|
| UniProt ID |
P02511
|
| Enzyme Class |
- |
| Molecular Weight |
20159 |
| Protein Length |
175 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm |
| Function (UniProt annotation) |
May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. |
| Gene Ontology |
GO:0001540; GO:0001666; GO:0002088; GO:0005212; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005794; GO:0005829; GO:0006457; GO:0006936; GO:0007021; GO:0007517; GO:0008017; GO:0009986; GO:0010259; GO:0010629; GO:0010941; GO:0014069; GO:0015630; GO:0030018; GO:0030308; GO:0030424; GO:0031109; GO:0031430; GO:0032355; GO:0032387; GO:0032432; GO:0032463; GO:0042542; GO:0042802; GO:0042803; GO:0043066; GO:0043154; GO:0043197; GO:0043204; GO:0043209; GO:0044877; GO:0046872; GO:0050821; GO:0051082; GO:0051260; GO:0051403; GO:0060561; GO:0070062; GO:0071480; GO:0097060; GO:0097512; GO:1900034; GO:1905907; GO:2000378 |
