| Gene |
LCP1
|
| Protein Name |
PLSL_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1) |
| Protein Family |
N/A |
| NCBI Gene ID |
3936
|
| UniProt ID |
P13796
|
| Enzyme Class |
- |
| Molecular Weight |
70288 |
| Protein Length |
627 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm, cytoskeleton |
| Function (UniProt annotation) |
Actin-binding protein (PubMed:16636079, PubMed:17294403, PubMed:28493397). Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403). Modulates the cell surface expression of IL2RA/CD25 and CD69 (PubMed:17294403). |
| Gene Ontology |
GO:0001726; GO:0001891; GO:0002102; GO:0002286; GO:0003779; GO:0005178; GO:0005509; GO:0005615; GO:0005737; GO:0005829; GO:0005884; GO:0005886; GO:0005925; GO:0010737; GO:0015629; GO:0016477; GO:0022617; GO:0030054; GO:0030175; GO:0031100; GO:0032432; GO:0032587; GO:0033157; GO:0035722; GO:0042802; GO:0051015; GO:0051017; GO:0051020; GO:0051639; GO:0070062; GO:0071803 |
