Graphics credits: COMPARTMENTS | More Info
Parameter | Value |
---|---|
Gene | TUBG1 |
Protein Name | TBG1_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) |
Protein Family | Tubulin family |
NCBI Gene ID | 7283 |
UniProt ID | P23258 |
Enzyme Class | - |
Molecular Weight | 51170 |
Protein Length | 451 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome |
Function (UniProt annotation) | Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation. |
Gene Ontology | GO:0000070; GO:0000086; GO:0000212; GO:0000226; GO:0000242; GO:0000278; GO:0000794; GO:0000930; GO:0003924; GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0005827; GO:0005829; GO:0005874; GO:0005881; GO:0007017; GO:0007020; GO:0007052; GO:0010389; GO:0031122; GO:0031252; GO:0036064; GO:0042802; GO:0045177; GO:0055037; GO:0097711; GO:0097730 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
BRSK1 (Q8TDC3) | Homo sapiens | S385 | MANHTSISSLFERTC | N/A | 0.268 | TP | certain | experimental | 74 | 9 | 55 | 73 | 76 | | 24942739 | - |
|
BRSK1 (Q8TDC3) | Homo sapiens | S131 | READGSDSLEGFVLC | N/A | 0.1501 | TP | certain | experimental | 72 | 55 | 76 | | 24942739 | - |
|
BRSK1 (Q8TDC3-2) | Homo sapiens | S131 | READGSDSLEGFVLC | N/A | 0.1501 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found