| Gene |
L1CAM
|
| Protein Name |
L1CAM_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171) |
| Protein Family |
Immunoglobulin superfamily |
| NCBI Gene ID |
3897
|
| UniProt ID |
P32004
|
| Enzyme Class |
- |
| Molecular Weight |
140003 |
| Protein Length |
1257 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cell membrane |
| Function (UniProt annotation) |
Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity. |
| Gene Ontology |
GO:0005886; GO:0005925; GO:0006935; GO:0007155; GO:0007156; GO:0007160; GO:0007399; GO:0007411; GO:0008046; GO:0009986; GO:0016021; GO:0016477; GO:0019904; GO:0030424; GO:0030425; GO:0031175; GO:0043025; GO:0044295; GO:0045773; GO:0050808; GO:0050900; GO:0061564; GO:0062023 |
