Graphics credits: COMPARTMENTS | More Info
Parameter | Value |
---|---|
Gene | KRT20 |
Protein Name | K1C20_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT) |
Protein Family | Intermediate filament family |
NCBI Gene ID | 54474 |
UniProt ID | P35900 |
Enzyme Class | - |
Molecular Weight | 48487 |
Protein Length | 424 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Cytoplasm |
Function (UniProt annotation) | Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). |
Gene Ontology | GO:0005200; GO:0005737; GO:0005829; GO:0005882; GO:0006915; GO:0009267; GO:0031424; GO:0045109; GO:0050708; GO:0070268 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Mapkapk2 (P49138) | Mus musculus | S13 | RSFHRSLSSSLQAPV | 0.855 | 0.3872 | TP | certain | experimental | 72 | 143 | 23 | | 20724476 | - |
|
MAPKAPK2 (P49137) | Homo sapiens | S13 | RSFHRSLSSSLQAPV | 0.855 | 0.3872 | - | - | - | - | - | - |
|
MAPKAPK3 (Q16644) | Homo sapiens | S13 | RSFHRSLSSSLQAPV | 0.855 | 0.3872 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found