| Gene |
Slc12a1
|
| Protein Name |
S12A1_MOUSE |
| Organism |
Mus musculus (Mouse) |
| Alternative name(s) |
Solute carrier family 12 member 1 (BSC1) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter) |
| Protein Family |
SLC12A transporter family |
| NCBI Gene ID |
20495
|
| UniProt ID |
P55014
|
| Enzyme Class |
- |
| Molecular Weight |
120355 |
| Protein Length |
1095 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Membrane; Multi-pass membrane protein. |
| Function (UniProt annotation) |
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume. |
| Gene Ontology |
GO:0001822; GO:0005886; GO:0006813; GO:0006814; GO:0006821; GO:0006884; GO:0007588; GO:0008511; GO:0009986; GO:0010107; GO:0015081; GO:0015378; GO:0015379; GO:0016021; GO:0016324; GO:0032978; GO:0034220; GO:0035725; GO:0048878; GO:0055064; GO:0055075; GO:0070062; GO:0070886; GO:0071475; GO:1902476 |
