Parameter | Value |
---|---|
Gene | Mybpc3 |
Protein Name | MYPC_RAT |
Organism | Rattus norvegicus (Rat) |
Alternative name(s) | Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform) |
Protein Family | Immunoglobulin superfamily |
NCBI Gene ID | 295929 |
UniProt ID | P56741 |
Enzyme Class | - |
Molecular Weight | 140762 |
Protein Length | 1274 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | N/A |
Function (UniProt annotation) | Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. |
Gene Ontology | GO:0005863; GO:0005865; GO:0006936; GO:0006942; GO:0007155; GO:0008307; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0031430; GO:0032036; GO:0042802; GO:0045214; GO:0046872; GO:0048739; GO:0051015; GO:0051371; GO:0055003; GO:0055008; GO:0055010; GO:0060048; GO:0097512 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
RPS6KA3 (P51812) | Homo sapiens | S288 | AGTGRRTSDSHEDAG | N/A | 0.6375 | - | - | - | - | - | - |
|
Reactome Pathways
KEGG Pathways
Pathway ID | Pathway Name |
---|---|
rno05410 | Hypertrophic cardiomyopathy (HCM) |
rno05414 | Dilated cardiomyopathy |
No NCI Nature pathways found