| Gene |
CYCS
|
| Protein Name |
CYC_BOVIN |
| Organism |
Bos taurus (Bovine) |
| Alternative name(s) |
Cytochrome c |
| Protein Family |
Cytochrome c family |
| NCBI Gene ID |
1.01E+14
|
| UniProt ID |
P62894
|
| Enzyme Class |
- |
| Molecular Weight |
11704 |
| Protein Length |
105 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane. |
| Function (UniProt annotation) |
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity). |
| Gene Ontology |
GO:0005758; GO:0006122; GO:0006123; GO:0006915; GO:0009055; GO:0020037; GO:0046872; GO:0070469 |
