| Gene |
Scarb1
|
| Protein Name |
SCRB1_RAT |
| Organism |
Rattus norvegicus (Rat) |
| Alternative name(s) |
Scavenger receptor class B member 1 (SRB1) (SR-BI) |
| Protein Family |
CD36 family |
| NCBI Gene ID |
25073
|
| UniProt ID |
P97943
|
| Enzyme Class |
- |
| Molecular Weight |
56957 |
| Protein Length |
509 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cell membrane |
| Function (UniProt annotation) |
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. |
| Gene Ontology |
GO:0001530; GO:0001540; GO:0001786; GO:0001875; GO:0001935; GO:0005319; GO:0005737; GO:0005886; GO:0005887; GO:0005901; GO:0006694; GO:0006702; GO:0006707; GO:0006869; GO:0006910; GO:0008035; GO:0009986; GO:0010867; GO:0010886; GO:0010899; GO:0015914; GO:0015920; GO:0030169; GO:0031528; GO:0032497; GO:0033344; GO:0034186; GO:0034375; GO:0034383; GO:0034384; GO:0035461; GO:0042632; GO:0042803; GO:0043231; GO:0043534; GO:0043654; GO:0043691; GO:0044406; GO:0050764; GO:0050892; GO:0051000; GO:0070328; GO:0070506; GO:0070508 |
