| Gene |
CREM
|
| Protein Name |
CREM_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
cAMP-responsive element modulator (Inducible cAMP early repressor) (ICER) |
| Protein Family |
BZIP family |
| NCBI Gene ID |
1390
|
| UniProt ID |
Q03060
|
| Enzyme Class |
- |
| Molecular Weight |
37006 |
| Protein Length |
345 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Nucleus.; Isoform 6: Cytoplasm |
| Function (UniProt annotation) |
Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550). |
| Gene Ontology |
GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0003677; GO:0005634; GO:0005667; GO:0005737; GO:0006006; GO:0006355; GO:0006631; GO:0006687; GO:0007165; GO:0007275; GO:0007283; GO:0008140; GO:0030154; GO:0042752; GO:0045944; GO:0048384; GO:0048511 |
