CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	MXD1
Protein Name	MAD1_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Max dimerization protein 1 (Max dimerizer 1) (Protein MAD)
Protein Family	N/A
NCBI Gene ID	4084
UniProt ID	Q05195
Enzyme Class	-
Molecular Weight	25254
Protein Length	221
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus.
Function (UniProt annotation)	Transcriptional repressor. MAD binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MAD thus antagonizes MYC transcriptional activity by competing for MAX.
Gene Ontology	GO:0000122; GO:0000790; GO:0000978; GO:0000981; GO:0001078; GO:0003700; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005739; GO:0005829; GO:0007275; GO:0008283; GO:0046983

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
RPS6KA1 (Q15418)	Homo sapiens	S145	IERIRMDSIGSTVSS	0.924	0.4979	-	-	-	-	-	-	In vitro and in vivo

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

NCI Nature PID Pathways

Pathway ID	Pathway Name
hdac_classi_pathway	Signaling events mediated by HDAC Class I
telomerasepathway	Regulation of Telomerase