| Gene |
CACNB2
|
| Protein Name |
CACB2_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB) |
| Protein Family |
Calcium channel beta subunit family |
| NCBI Gene ID |
783
|
| UniProt ID |
Q08289
|
| Enzyme Class |
- |
| Molecular Weight |
73581 |
| Protein Length |
660 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cell membrane, sarcolemma |
| Function (UniProt annotation) |
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. |
| Gene Ontology |
GO:0005245; GO:0005262; GO:0005886; GO:0005887; GO:0005891; GO:0007268; GO:0007528; GO:0007601; GO:0008331; GO:0051015; GO:0051928; GO:0070509; GO:0072659; GO:0086045; GO:0086091; GO:0098684; GO:0098793; GO:0098912; GO:0099635; GO:1901385; GO:1901843; GO:1904879; GO:1990454 |
