| Gene |
Hif3a
|
| Protein Name |
HIF3A_MOUSE |
| Organism |
Mus musculus (Mouse) |
| Alternative name(s) |
Hypoxia-inducible factor 3-alpha (HIF-3-alpha) (HIF3-alpha) (Basic-helix-loop-helix-PAS protein MOP7) (HIF3-alpha-1) (Inhibitory PAS domain protein) (IPAS) (Member of PAS protein 7) (Neonatal and embryonic PAS protein) |
| Protein Family |
N/A |
| NCBI Gene ID |
53417
|
| UniProt ID |
Q0VBL6
|
| Enzyme Class |
- |
| Molecular Weight |
73044 |
| Protein Length |
662 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Nucleus |
| Function (UniProt annotation) |
Acts as a transcriptional regulator in adaptive response to low oxygen tension. Acts as a regulator of hypoxia-inducible gene expression (PubMed:9840812, PubMed:11734856, PubMed:21546903). Plays a role in the development of the cardiorespiratory system (PubMed:18070924). |
| Gene Ontology |
GO:0000981; GO:0001525; GO:0001666; GO:0003677; GO:0003700; GO:0003713; GO:0003714; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006357; GO:0006366; GO:0006915; GO:0016607; GO:0045944; GO:0046983 |
