Graphics credits: COMPARTMENTS | More Info
Parameter | Value |
---|---|
Gene | CTBP1 |
Protein Name | CTBP1_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) |
Protein Family | D-isomer specific 2-hydroxyacid dehydrogenase family |
NCBI Gene ID | 1487 |
UniProt ID | Q13363 |
Enzyme Class | 1.1.1.- |
Molecular Weight | 47535 |
Protein Length | 440 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Cytoplasm |
Function (UniProt annotation) | Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. |
Gene Ontology | GO:0000122; GO:0003700; GO:0003714; GO:0005634; GO:0005654; GO:0005667; GO:0006468; GO:0008022; GO:0008134; GO:0008285; GO:0016616; GO:0017053; GO:0019079; GO:0019904; GO:0031065; GO:0035067; GO:0042802; GO:0045892; GO:0050872; GO:0051287; GO:0051726; GO:0070491; GO:0090241; GO:0098831; GO:0098978; GO:0098982; GO:1903758 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
PRKAA1 (Q13131) | Homo sapiens | S158 | REGTRVQSVEQIREV | 0.085 | 0.3392 | TP | certain | experimental | 23 | 72 | 30 | 55 | | 23291169 | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found