| Gene |
ITPR2
|
| Protein Name |
ITPR2_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor) |
| Protein Family |
InsP3 receptor family |
| NCBI Gene ID |
3709
|
| UniProt ID |
Q14571
|
| Enzyme Class |
- |
| Molecular Weight |
308064 |
| Protein Length |
2701 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Function (UniProt annotation) |
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity). |
| Gene Ontology |
GO:0001666; GO:0005220; GO:0005509; GO:0005634; GO:0005783; GO:0005789; GO:0005886; GO:0005938; GO:0007165; GO:0015085; GO:0016020; GO:0016021; GO:0016529; GO:0030168; GO:0030659; GO:0030667; GO:0031095; GO:0033017; GO:0035091; GO:0043235; GO:0050796; GO:0051209; GO:0070679; GO:0071320; GO:0071361; GO:0097110; GO:1903779 |
