CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	DIXDC1
Protein Name	DIXC1_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1)
Protein Family	DIXDC1 family
NCBI Gene ID	85458
UniProt ID	Q155Q3
Enzyme Class	-
Molecular Weight	77478
Protein Length	683
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cell junction, focal adhesion
Function (UniProt annotation)	Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.
Gene Ontology	GO:0003779; GO:0005829; GO:0005856; GO:0005925; GO:0019904; GO:0021799; GO:0021869; GO:0030177; GO:0032956; GO:0043015; GO:0045665; GO:0060070; GO:0070507

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MARK1 (Q9P0L2)	Homo sapiens	S592	SKLPHSQSSPTVSST	0.462	0.8235	-	-	-	-	-	-	in-vivo

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found