CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	PPP1R3A
Protein Name	PPR3A_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RG1)
Protein Family	N/A
NCBI Gene ID	5506
UniProt ID	Q16821
Enzyme Class	-
Molecular Weight	125767
Protein Length	1122
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Membrane
Function (UniProt annotation)	Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase (By similarity).
Gene Ontology	GO:0005977; GO:0016021

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
RPS6KA3 (P51812)	Homo sapiens	S46	PQPSRRGSDSSEDIY	0.836	0.5758	-	-	-	-	-	-	In vitro
RPS6KA3 (P51812)	Homo sapiens	S65	SSGTRRVSFADSFGF	0.811	0.268	-	-	-	-	-	-	In vitro
RPS6KA1 (Q15418)	Homo sapiens	S48	PSRRGSDSSEDIYLD	0.774	0.7415	-	-	-	-	2152882	Non high throughput (2152882)	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa04910	Insulin signaling pathway

NCI Nature PID Pathways

Pathway ID	Pathway Name
insulin_glucose_pathway	Insulin-mediated glucose transport