| Gene |
Myl12b
|
| Protein Name |
ML12B_MOUSE |
| Organism |
Mus musculus (Mouse) |
| Alternative name(s) |
Myosin regulatory light chain 12B (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) |
| Protein Family |
N/A |
| NCBI Gene ID |
67938
|
| UniProt ID |
Q3THE2
|
| Enzyme Class |
- |
| Molecular Weight |
19779 |
| Protein Length |
172 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
N/A |
| Function (UniProt annotation) |
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion. |
| Gene Ontology |
GO:0001725; GO:0005509; GO:0005903; GO:0008360; GO:0016460; GO:0030018; GO:0032036; GO:0032991; GO:0045177; GO:0099738 |
