| Gene |
Nfe2l2
|
| Protein Name |
NF2L2_MOUSE |
| Organism |
Mus musculus (Mouse) |
| Alternative name(s) |
Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) |
| Protein Family |
BZIP family |
| NCBI Gene ID |
18024
|
| UniProt ID |
Q60795
|
| Enzyme Class |
- |
| Molecular Weight |
66901 |
| Protein Length |
597 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm, cytosol |
| Function (UniProt annotation) |
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress and the regulation of cellular redox conditions. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region. |
| Gene Ontology |
GO:0000785; GO:0000976; GO:0000980; GO:0001102; GO:0001205; GO:0001221; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005813; GO:0005829; GO:0005886; GO:0006355; GO:0006954; GO:0007568; GO:0008134; GO:0010499; GO:0010628; GO:0010667; GO:0010976; GO:0016567; GO:0019904; GO:0030194; GO:0030968; GO:0032993; GO:0034599; GO:0034976; GO:0035690; GO:0036003; GO:0036091; GO:0036499; GO:0042149; GO:0043161; GO:0043536; GO:0043565; GO:0045454; GO:0045766; GO:0045893; GO:0045944; GO:0045995; GO:0046223; GO:0046326; GO:0046982; GO:0060548; GO:0061419; GO:0070301; GO:0071356; GO:0071498; GO:0071499; GO:1902037; GO:1902176; GO:1903206; GO:1903788; GO:1904385; GO:1904753; GO:2000121; GO:2000352; GO:2000379 |
