| Gene |
Ksr1
|
| Protein Name |
KSR1_MOUSE |
| Organism |
Mus musculus (Mouse) |
| Alternative name(s) |
Kinase suppressor of Ras 1 (mKSR1) (Protein Hb) |
| Protein Family |
Protein kinase superfamily |
| NCBI Gene ID |
16706
|
| UniProt ID |
Q61097
|
| Enzyme Class |
- |
| Molecular Weight |
96755 |
| Protein Length |
873 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm |
| Function (UniProt annotation) |
Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases (PubMed:10409742, PubMed:12932319, PubMed:21102438). Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP (PubMed:21102438). Does not have kinase activity by itself (Probable). |
| Gene Ontology |
GO:0004672; GO:0005078; GO:0005524; GO:0005783; GO:0005789; GO:0007265; GO:0008022; GO:0016020; GO:0019933; GO:0031434; GO:0032587; GO:0032991; GO:0042127; GO:0043405; GO:0043410; GO:0046872; GO:0051087; GO:0051879; GO:0071889 |
