CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	STRADA
Protein Name	STRAA_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein) (Serologically defined breast cancer antigen NY-BR-96)
Protein Family	Protein kinase superfamily
NCBI Gene ID	92335
UniProt ID	Q7RTN6
Enzyme Class	-
Molecular Weight	48369
Protein Length	431
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus
Function (UniProt annotation)	Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Gene Ontology	GO:0000165; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006611; GO:0007050; GO:0019900; GO:0023014; GO:0030295; GO:0031098; GO:0032147; GO:0043539; GO:0048812

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
STK11 (Q15831)	Homo sapiens	T329	GLSDSLTTSTPRPSN	0.11	0.805	TP	certain	experimental	23 \| 72 \| 73 \| 30 \| 133 \| 135 \| 9 \|	12805220	-	-
STK11 (Q15831)	Homo sapiens	T419	SGIFGLVTNLEELEV	0.145	0.346	TP	certain	experimental	23 \| 72 \| 73 \| 30 \| 133 \| 135 \| 9 \|	12805220	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa04150	mTOR signaling pathway

No NCI Nature pathways found