CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	Eif4b
Protein Name	IF4B_MOUSE
Organism	Mus musculus (Mouse)
Alternative name(s)	Eukaryotic translation initiation factor 4B (eIF-4B)
Protein Family	N/A
NCBI Gene ID	75705
UniProt ID	Q8BGD9
Enzyme Class	-
Molecular Weight	68840
Protein Length	611
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	N/A
Function (UniProt annotation)	Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F (By similarity).
Gene Ontology	GO:0001731; GO:0002181; GO:0003743; GO:0005829; GO:0005844; GO:0030425; GO:0033592; GO:0034057; GO:0043024; GO:0043025; GO:0097010; GO:0098794

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
RPS6KA1 (Q15418)	Homo sapiens	S422	RERSRTGSESSQTGA	N/A	0.9503	-	-	-	-	-	-	In vivo

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
mmu03013	RNA transport
mmu04150	mTOR signaling pathway

No NCI Nature pathways found