| Gene |
Erc2
|
| Protein Name |
ERC2_RAT |
| Organism |
Rattus norvegicus (Rat) |
| Alternative name(s) |
ERC protein 2 (CAZ-associated structural protein 1) (CAST1) (Cast) (Cytomatrix protein p110) |
| Protein Family |
N/A |
| NCBI Gene ID |
259269
|
| UniProt ID |
Q8K3M6
|
| Enzyme Class |
- |
| Molecular Weight |
110618 |
| Protein Length |
957 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm. Cell junction, synapse. Cell junction, synapse, synaptosome. Cytoplasm, cytoskeleton. Note=Localized to the active zone of presynaptic density. Colocalizes with RIMS1 and BSN in early stages of synapse formation. |
| Function (UniProt annotation) |
Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ. |
| Gene Ontology |
GO:0005783; GO:0005856; GO:0007416; GO:0014069; GO:0016020; GO:0030054; GO:0030165; GO:0030426; GO:0032991; GO:0042734; GO:0043025; GO:0043195; GO:0044877; GO:0045202; GO:0050808; GO:0098831 |
