CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	39692
Protein Name	SEPT8_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Septin-8
Protein Family	TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily
NCBI Gene ID	23176
UniProt ID	Q92599
Enzyme Class	-
Molecular Weight	55756
Protein Length	483
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cytoplasm
Function (UniProt annotation)	Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion.
Gene Ontology	GO:0000281; GO:0000921; GO:0003924; GO:0005525; GO:0005940; GO:0015630; GO:0031105; GO:0032160; GO:0032947; GO:0060271

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MAPKAPK5 (Q8IW41)	Homo sapiens	S192	IAKADTISKSELHKF	0.363	0.1028	TP	certain	experimental	66 \| 40 \| 74 \| 55 \| 72 \| 9 \| 144 \|	22649572	-	-
MAPKAPK5 (Q8IW41)	Homo sapiens	T158	HVCLYFITPTGHSLK	0.005	0.087	TP	certain	experimental	66 \| 40 \| 74 \| 55 \| 72 \| 9 \| 144 \|	22649572	-	-
MAPKAPK5 (Q8IW41)	Homo sapiens	S163	FITPTGHSLKSLDLV	0.129	0.0662	-	-	-	-	-	-	In vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found