Graphics credits: COMPARTMENTS | More Info
| Parameter | Value |
|---|---|
| Gene | DAZL |
| Protein Name | DAZL_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Deleted in azoospermia-like (DAZ homolog) (DAZ-like autosomal) (Deleted in azoospermia-like 1) (SPGY-like-autosomal) |
| Protein Family | RRM DAZ family |
| NCBI Gene ID | 1618 |
| UniProt ID | Q92904 |
| Enzyme Class | - |
| Molecular Weight | 33178 |
| Protein Length | 295 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Cytoplasm |
| Function (UniProt annotation) | RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity). |
| Gene Ontology | GO:0001556; GO:0003723; GO:0003730; GO:0005622; GO:0005634; GO:0005737; GO:0005844; GO:0007147; GO:0007275; GO:0007281; GO:0007283; GO:0008494; GO:0032991; GO:0042802; GO:0045836; GO:0045948 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MAPKAPK2 (P49137) | Homo sapiens | S65 | SFFARYGSVKEVKII | 0.026 | 0.2258 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found