CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	CIC
Protein Name	CIC_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Protein capicua homolog
Protein Family	N/A
NCBI Gene ID	23152
UniProt ID	Q96RK0
Enzyme Class	-
Molecular Weight	163820
Protein Length	1608
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus
Function (UniProt annotation)	Transcriptional repressor which plays a role in development of the central nervous system (CNS). In concert with ATXN1 and ATXN1L, involved in brain development.
Gene Ontology	GO:0000122; GO:0000981; GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
RPS6KA3 (P51812)	Homo sapiens	S173	PGKRRTQSLSALPKE	0.36	0.892	-	-	-	-	-	-	In vitro
RPS6KA1 (Q15418)	Homo sapiens	S173	PGKRRTQSLSALPKE	0.36	0.892	-	-	-	-	-	-	In vitro and in vivo

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found