| Gene |
Ube2j1
|
| Protein Name |
UB2J1_MOUSE |
| Organism |
Mus musculus (Mouse) |
| Alternative name(s) |
Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) |
| Protein Family |
Ubiquitin-conjugating enzyme family |
| NCBI Gene ID |
56228
|
| UniProt ID |
Q9JJZ4
|
| Enzyme Class |
2.3.2.23 |
| Molecular Weight |
34990 |
| Protein Length |
318 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine. |
| Localization |
Endoplasmic reticulum membrane |
| Function (UniProt annotation) |
Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). |
| Gene Ontology |
GO:0005524; GO:0005789; GO:0007286; GO:0016021; GO:0018279; GO:0030433; GO:0031625; GO:0042534; GO:0061631; GO:1904153 |
