| Gene |
ACSS2
|
| Protein Name |
ACSA_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme) |
| Protein Family |
ATP-dependent AMP-binding enzyme family |
| NCBI Gene ID |
55902
|
| UniProt ID |
Q9NR19
|
| Enzyme Class |
6.2.1.1 |
| Molecular Weight |
78580 |
| Protein Length |
701 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. |
| Localization |
Cytoplasm. |
| Function (UniProt annotation) |
Activates acetate so that it can be used for lipid synthesis or for energy generation. |
| Gene Ontology |
GO:0003987; GO:0005524; GO:0005654; GO:0005737; GO:0005759; GO:0005829; GO:0006069; GO:0008610; GO:0016208; GO:0019413; GO:0019427; GO:0019542; GO:0043231 |
