CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	NDRG2
Protein Name	NDRG2_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Protein NDRG2 (N-myc downstream-regulated gene 2 protein) (Protein Syld709613)
Protein Family	NDRG family
NCBI Gene ID	57447
UniProt ID	Q9UN36
Enzyme Class	-
Molecular Weight	40798
Protein Length	371
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone
Function (UniProt annotation)	Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.
Gene Ontology	GO:0001818; GO:0005634; GO:0005737; GO:0005794; GO:0005829; GO:0007165; GO:0010574; GO:0016055; GO:0021762; GO:0030154; GO:0030426; GO:0048471; GO:0048662; GO:0070062; GO:0070373; GO:0090361

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
RPS6KA1 (Q15418)	Homo sapiens	S332	LSRSRTASLTSAASV	0.542	0.5533	-	-	-	-	-	-	In vitro
RPS6KA1 (Q15418)	Homo sapiens	S350	RSRSRTLSQSSESGT	0.882	0.7843	-	-	-	-	-	-	In vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found