CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	PPP1R3C
Protein Name	PPR3C_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Protein phosphatase 1 regulatory subunit 3C (Protein phosphatase 1 regulatory subunit 5) (PP1 subunit R5) (Protein targeting to glycogen) (PTG)
Protein Family	N/A
NCBI Gene ID	5507
UniProt ID	Q9UQK1
Enzyme Class	-
Molecular Weight	36445
Protein Length	317
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	N/A
Function (UniProt annotation)	Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.
Gene Ontology	GO:0004722; GO:0005829; GO:0005977; GO:0005978; GO:0019888; GO:0019903

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
PRKAA1 (Q13131)	Homo sapiens	S293	LESTIFGSPRLASGL	0.839	0.3149	-	-	-	-	-	-	In vivo
PRKAA1 (Q13131)	Homo sapiens	S33	MRLCLAHSPPVKSFL	0.979	0.1298	-	-	-	-	-	-	In vivo

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa04910	Insulin signaling pathway

No NCI Nature pathways found