Graphics credits: COMPARTMENTS | More Info
Parameter | Value |
---|---|
Gene | IRS2 |
Protein Name | IRS2_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | Insulin receptor substrate 2 (IRS-2) |
Protein Family | N/A |
NCBI Gene ID | 8660 |
UniProt ID | Q9Y4H2 |
Enzyme Class | - |
Molecular Weight | 137334 |
Protein Length | 1338 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Cytoplasm, cytosol |
Function (UniProt annotation) | May mediate the control of various cellular processes by insulin. |
Gene Ontology | GO:0000165; GO:0002053; GO:0002903; GO:0005088; GO:0005158; GO:0005829; GO:0005886; GO:0006006; GO:0007165; GO:0007411; GO:0007420; GO:0008283; GO:0008284; GO:0008286; GO:0009749; GO:0010748; GO:0010907; GO:0016303; GO:0019216; GO:0019901; GO:0019903; GO:0019904; GO:0030335; GO:0030879; GO:0030890; GO:0032000; GO:0032024; GO:0032869; GO:0032991; GO:0033673; GO:0038111; GO:0043548; GO:0045725; GO:0046326; GO:0046934; GO:0048015; GO:0051897; GO:0055088; GO:0071333; GO:0071889 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
PIM1 (P11309) | Homo sapiens | S1149 | GGRRRHSSETFSSTT | 0.742 | 0.9287 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found