Protein Name
MAP kinase-interacting serine/threonine-protein kinase 1
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
51,342
Protein Length
465
Protein Domain
3D Structure
(PDB ID : 2hw6)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
Catalytic Site
Catalytic Activity
ATP + a protein = ADP + a phosphoprotein.
Localization
Isoform 2: Cytoplasm.; Isoform 3: Cytoplasm. Nucleus.
Function
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Gene Ontology
GO:0004674; GO:0004683; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006417; GO:0006468; GO:0009931; GO:0018105; GO:0035556; GO:0046872
