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| Parameter | Value |
|---|---|
| Gene | CACNA1C |
| Protein Name | F5H522_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Voltage-dependent L-type calcium channel subunit alpha |
| Protein Family | Calcium channel alpha-1 subunit (TC 1.A.1.11) family |
| NCBI Gene ID | 775 |
| UniProt ID | F5H522 |
| Enzyme Class | - |
| Molecular Weight | 242406 |
| Protein Length | 2163 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Membrane |
| Function (UniProt annotation) | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. |
| Gene Ontology | GO:0005245; GO:0005891; GO:0034765 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK2A (Q9UQM7) | Homo sapiens | S1512 | DYLTRDWSILGPHHL | N/A | 0.0676 | - | - | - | - | - | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S1570 | VACKRLVSMNMPLNS | N/A | 0.2715 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found