CaMKipedia | Result

Graphics credits: COMPARTMENTS | More Info

Sequence Viewer

Gene

CAMK2A

Synonyms

CAMKA KIAA0968

Protein Name

Calcium/calmodulin-dependent protein kinase type II subunit alpha

UniProt ID

Q9UQM7

Ensembl Gene ID

9606.ENSP00000381412

NCBI Gene ID

815

Molecular Weight

54,088

Protein Length

478

Protein Domain

InterPro | Pfam

3D Structure
(PDB ID : 3soa)

PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

2.7.11.17 (BRENDA)

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

ATP + a protein = ADP + a phosphoprotein.

Localization

Cell junction, synapse Cell junction, synapse, postsynaptic cell membrane, postsynaptic density Cell projection, dendritic spine Cell projection, dendrite Note=Postsynaptic lipid rafts.

Function

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development (PubMed:28130356). Also regulates the migration of developing neurons (PubMed:29100089). Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378).

Gene Ontology

GO:0000082; GO:0000165; GO:0002931; GO:0004674; GO:0004683; GO:0005088; GO:0005516; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0005954; GO:0006468; GO:0006816; GO:0007223; GO:0009931; GO:0010666; GO:0014069; GO:0016301; GO:0018105; GO:0030054; GO:0030666; GO:0035254; GO:0038166; GO:0042802; GO:0042803; GO:0043005; GO:0043197; GO:0045211; GO:0046777; GO:0046872; GO:0046928; GO:0048168; GO:0048813; GO:0051092; GO:0051928; GO:0060333; GO:0060996; GO:0098685; GO:0099148; GO:1902108; GO:1990443; GO:2001222

Gene Ontology

Substrate	Organism	PSite	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
KCND2 (Q9NZV8)	Homo sapiens	S459	LLSNQLQSSEDEQAF	0.097	0.4441	TP	certain	experimental	73 \| 273 \| 135 \| 62 \|	15071113	-	-
Nos1 (Q9Z0J4)	Mus musculus	S847	SYKVRFNSVSSYSDS	-	0.3426	TP	certain	experimental	72 \| 73 \| 55 \|	12630910	-	-
PLCB3 * (Q01970)	Homo sapiens	S537	PSLEPQKSLGDEGLN	0.766	0.8681	TP	certain	experimental	72 \| 107 \| 62 \|	11325525	-	-
Nlgn1 (Q99K10)	Mus musculus	T739	CSPQRTTTNDLTHAP	-	0.8741	TP	certain	experimental	72 \| 9 \| 31 \| 73 \| 55 \|	24336150	-	-
Ryr2 (B0LPN4)	Rattus norvegicus	S2798	YNRTRRISQTSQVSI	-	0.3215	-	-	-	-	-	-	In vitro
Ryr2 (B0LPN4)	Rattus norvegicus	S2804	ISQTSQVSIDAAHGY	-	0.4725	-	-	-	-	-	-	In vitro
Ryr2 (E9Q401)	Mus musculus	S2807	YNRTRRISQTSQVSI	-	0.3149	-	-	-	-	-	-	In vivo
Trpv1 (O35433)	Rattus norvegicus	S502	YFLQRRPSLKSLFVD	-	0.0088	-	-	-	-	-	-	In vivo
Syn1 (O88935)	Mus musculus	S605	AGPTRQASQAGPGPR	-	0.9924	-	-	-	-	-	-	In vivo
EGFR (P00533)	Homo sapiens	S1070	DSFLQRYSSDPTGAL	0.5	0.5807	-	-	-	-	10347170	Non high throughput (10347170)	-
EGFR (P00533)	Homo sapiens	S1071	SFLQRYSSDPTGALT	0.5	0.6755	-	-	-	-	10347170	Non high throughput (10347170)	-
EGFR (P00533)	Homo sapiens	S1081	TGALTEDSIDDTFLP	0.5	0.7209	-	-	-	-	10347170	Non high throughput (10347170)	-
EGFR (P00533)	Homo sapiens	S1166	QKGSHQISLDNPDYQ	0.452	0.6089	-	-	-	-	10347170	Non high throughput (10347170)	-
EGFR (P00533)	Homo sapiens	S768	DEAYVMASVDNPHVC	0.574	0.0734	-	-	-	-	10347170	Non high throughput (10347170)	-
NEFL (P02548)	Bos taurus	S58	LSVRRSYSSSSGSLM	-	0.3983	-	-	-	-	-	-	In vitro
NEFL (P02548)	Bos taurus	S67	SSGSLMPSLESLDLS	-	0.3566	-	-	-	-	-	-	In vitro
NEFL (P02548)	Bos taurus	S70	SLMPSLESLDLSQVA	-	0.3286	-	-	-	-	-	-	In vitro
TH (P07101)	Homo sapiens	S19	KGFRRAVSELDAKQA	0.455	0.5758	-	-	-	-	1680128	Non high throughput (1680128)	In vitro and in vivo
TH (P07101)	Homo sapiens	S71	RFIGRRQSLIEDARK	0.945	0.6269	-	-	-	-	1680128	Non high throughput (1680128)	In vitro
TH (P07101-3)	Homo sapiens	S40	RFIGRRQSLIEDARK	-	-	-	-	-	-	-	-	In vitro
CACNA1S (P07293)	Oryctolagus cuniculus	S1575	PEIRRTISGDLTAEE	-	0.5577	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S244	KDRVKGRSDPYHATT	-	0.4725	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S330	AGSTISNSHAQPFDF	-	0.725	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S364	AIVDQRPSSRASSRA	-	0.805	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S365	IVDQRPSSRASSRAS	-	0.8198	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S369	RPSSRASSRASSRPR	-	0.9396	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S372	SRASSRASSRPRPDD	-	0.8828	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S373	RASSRASSRPRPDDL	-	0.8765	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S255	HATTGPLSPSKDCGS	-	0.4369	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S257	TTGPLSPSKDCGSPK	-	0.2884	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S296	VTGDRNNSSCRNYNK	-	0.4582	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S297	TGDRNNSSCRNYNKQ	-	0.5665	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S306	RNYNKQASEQNWANY	-	0.4507	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S314	EQNWANYSAEQNRMG	-	0.6576	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S325	NRMGQAGSTISNSHA	-	0.7547	-	-	-	-	-	-	In vitro
Gja1 (P08050)	Rattus norvegicus	S328	GQAGSTISNSHAQPF	-	0.708	-	-	-	-	-	-	In vitro
VIM (P08670)	Homo sapiens	S83	GVRLLQDSVDFSLAD	0.105	0.2918	-	-	-	-	16140754, 9794428	Non high throughput (16140754, 9794428)	In vivo
ALOX5 (P09917)	Homo sapiens	S272	CSLERQLSLEQEVQQ	0.144	0.1914	-	-	-	-	11844797	Non high throughput (11844797)	In vitro
MPZ (P10522)	Bos taurus	S210	HKTAKDASKRGRQTP	-	0.4541	-	-	-	-	-	-	In vitro
MPZ (P10522)	Bos taurus	S233	SRSTKAASEKKTKGL	-	0.5758	-	-	-	-	-	-	In vitro
MAPT (P10636-8)	Homo sapiens	S262	NVKSKIGSTENLKHQ	-	-	-	-	-	-	-	-	In vitro
MAPT (P10636-8)	Homo sapiens	S416	SNVSSTGSIDMVDSP	-	-	-	-	-	-	-	-	In vitro
Camk2a (P11275)	Rattus norvegicus	S314	MLATRNFSGGKSGGN	-	0.5211	-	-	-	-	-	-	In vitro
Mylk (P11799)	Gallus gallus	S1749	RAIGRLSSMAMISGM	-	0.3774	-	-	-	-	-	-	In vitro
Mylk (P11799)	Gallus gallus	S1762	GMSGRKASGSSPTSP	-	0.6227	-	-	-	-	-	-	In vitro
SRF (P11831)	Homo sapiens	S103	RGLKRSLSEMEIGMV	0.283	0.5017	-	-	-	-	-	-	In vitro
CALD1 (P12957)	Gallus gallus	S26	RLEAERLSYQRNDDD	-	0.6948	-	-	-	-	-	-	In vitro
CALD1 (P12957)	Gallus gallus	S490	LTTPKLKSTENAFGR	-	0.7459	-	-	-	-	-	-	In vitro
CALD1 (P12957)	Gallus gallus	S59	QKEEGDVSGEVTEKS	-	0.6948	-	-	-	-	-	-	In vitro
CALD1 (P12957)	Gallus gallus	S602	CFSPKGSSLKIEERA	-	0.422	-	-	-	-	-	-	In vitro
CALD1 (P12957)	Gallus gallus	S635	AVVSKIDSRLEQYTS	-	0.5176	-	-	-	-	-	-	In vitro
CALD1 (P12957)	Gallus gallus	S73	SEVNAQNSVAEEETK	-	0.8198	-	-	-	-	-	-	In vitro
CALD1 (P12957)	Gallus gallus	S741	RNLWEKQSVEKPAAS	-	0.7547	-	-	-	-	-	-	In vitro
ETS1 (P14921)	Homo sapiens	S251	GKLGGQDSFESIESY	0.994	0.4087	-	-	-	-	12475968	Non high throughput (12475968)	In vitro and in vivo
ETS1 (P14921)	Homo sapiens	S257	DSFESIESYDSCDRL	0.404	0.4369	-	-	-	-	12475968	Non high throughput (12475968)	In vitro and in vivo
ETS1 (P14921)	Homo sapiens	S282	NSLQRVPSYDSFDSE	0.369	0.3774	-	-	-	-	12475968	Non high throughput (12475968)	In vitro and in vivo
ETS1 (P14921)	Homo sapiens	S285	QRVPSYDSFDSEDYP	0.381	0.3774	-	-	-	-	12475968	Non high throughput (12475968)	In vitro and in vivo
ETS2 (P15036)	Homo sapiens	S246	FPKSRLSSVSVTYCS	0.04	0.1969	-	-	-	-	-	-	In vitro
ETS2 (P15036)	Homo sapiens	S310	LDVQRVPSFESFEDD	0.627	0.3249	-	-	-	-	-	-	In vitro and in vivo
ETS2 (P15036)	Homo sapiens	S313	QRVPSFESFEDDCSQ	0.957	0.2503	-	-	-	-	-	-	In vitro and in vivo
Lipe (P15304)	Rattus norvegicus	S865	ESMRRSVSEAALAQP	-	0.5901	-	-	-	-	-	-	In vitro
Creb1 (P15337)	Rattus norvegicus	S133	EILSRRPSYRKILND	-	0.5055	-	-	-	-	-	-	In vitro and in vivo
Creb1 (P15337)	Rattus norvegicus	S142	RKILNDLSSDAPGVP	-	0.5807	-	-	-	-	-	-	In vitro
CACNA1C (P15381)	Oryctolagus cuniculus	S1517	DYLTRDWSILGPHHL	-	0.0662	-	-	-	-	-	-	In vitro
CACNA1C (P15381)	Oryctolagus cuniculus	S1575	VACKRLVSMNMPLNS	-	0.2715	-	-	-	-	-	-	In vitro
CACNA1C (P15381)	Oryctolagus cuniculus	S1700	PEIRRAISGDLTAEE	-	0.4979	-	-	-	-	-	-	In vitro
CACNA1C (P15381)	Oryctolagus cuniculus	S439	GVLSGEFSKEREKAK	-	0.2988	-	-	-	-	-	-	In vitro
CACNA1C (P15381-4)	Oryctolagus cuniculus	S1512	DYLTRDWSILGPHHL	-	-	-	-	-	-	-	-	In vitro
CACNA1C (P15381-4)	Oryctolagus cuniculus	S1570	VACKRLVSMNMPLNS	-	-	-	-	-	-	-	-	In vitro
CD44 (P16070)	Homo sapiens	S706	LNGEASKSQEMVHLV	0.797	0.6948	-	-	-	-	-	-	In vitro and in vivo
SYN1 (P17599)	Bos taurus	S605	AGPTRQASQAGPMPR	-	0.9921	-	-	-	-	-	-	In vitro
Ptpra (P18052)	Mus musculus	S180	QAGSHSNSFRLSNGR	-	0.5665	-	-	-	-	-	-	In vitro
Ptpra (P18052)	Mus musculus	S204	PLLARSPSTNRKYPP	-	0.4685	-	-	-	-	-	-	In vitro
Spr (P18297)	Rattus norvegicus	S196	EPSVRVLSYAPGPLD	-	0.3599	-	-	-	-	-	-	In vitro
Spr (P18297)	Rattus norvegicus	S214	QQLARETSMDPELRS	-	0.5296	-	-	-	-	-	-	In vitro
Spr (P18297)	Rattus norvegicus	S46	LLSARSDSMLRQLKE	-	0.107	-	-	-	-	-	-	In vitro
Drd3 (P19020)	Rattus norvegicus	S229	RILTRQNSQCISIRP	-	0.3087	-	-	-	-	-	-	In vitro
Gria1 (P19490)	Rattus norvegicus	S645	LTVERMVSPIESAED	-	0.1323	-	-	-	-	-	-	In vitro
Gria1 (P19490)	Rattus norvegicus	S849	FCLIPQQSINEAIRT	-	0.1942	-	-	-	-	-	-	In vitro
Gria4 (P19493)	Rattus norvegicus	S862	TRNKARLSITGSVGE	-	0.4901	-	-	-	-	-	-	In vitro
FLNA (P21333)	Homo sapiens	S2523	VTGPRLVSNHSLHET	0.139	0.5139	-	-	-	-	-	-	In vivo
Gabrg2 (P22723)	Mus musculus	S381	NPLLRMFSFKAPTID	-	0.0948	-	-	-	-	8027073	Non high throughput (8027073)	-
Gabrg2 (P22723)	Mus musculus	S393	TIDIRPRSATIQMNN	-	0.3494	-	-	-	-	8027073	Non high throughput (8027073)	-
Gria1 (P23818)	Mus musculus	S849	FCLIPQQSINEAIRT	-	0.1942	-	-	-	-	-	-	In vitro
Gjc1 (P28229)	Mus musculus	S326	AQEQQYGSHEEHLPA	-	0.5758	-	-	-	-	-	-	In vitro
Gjc1 (P28229)	Mus musculus	S381	SKSGSNKSSISSKSG	-	0.7755	-	-	-	-	-	-	In vitro
Gjc1 (P28229)	Mus musculus	S382	KSGSNKSSISSKSGD	-	0.7755	-	-	-	-	-	-	In vitro
Gjc1 (P28229)	Mus musculus	S384	GSNKSSISSKSGDGK	-	0.7755	-	-	-	-	-	-	In vitro
Gjc1 (P28229)	Mus musculus	S385	SNKSSISSKSGDGKT	-	0.6661	-	-	-	-	-	-	In vitro
Gjc1 (P28229)	Mus musculus	S387	KSSISSKSGDGKTSV	-	0.5707	-	-	-	-	-	-	In vitro
Gjc1 (P28229)	Mus musculus	S393	KSGDGKTSVWI____	-	0.4292	-	-	-	-	-	-	In vitro
MAPT (P29172)	Bos taurus	S423	SNVSSTGSIDMVDSP	-	0.5665	-	-	-	-	-	-	In vitro
NOS1 (P29475)	Homo sapiens	S852	SYKVRFNSVSSYSDS	0.88	0.3529	-	-	-	-	10400690, 10874031, 12630910	Non high throughput (10400690, 10874031, 12630910)	-
Nos1 (P29476)	Rattus norvegicus	S847	SYKVRFNSVSSYSDS	-	0.3426	-	-	-	-	-	-	In vivo
Vim (P31000)	Rattus norvegicus	S39	TTSTRTYSLGSALRP	-	0.4766	-	-	-	-	-	-	In vitro
Dlg4 (P31016)	Rattus norvegicus	S73	ITLERGNSGLGFSIA	-	0.3704	-	-	-	-	-	-	In vitro and in vivo
Oprm1 (P33535)	Rattus norvegicus	S261	LMILRLKSVRMLSGS	-	0.0141	-	-	-	-	-	-	In vivo
Oprm1 (P33535)	Rattus norvegicus	S266	LKSVRMLSGSKEKDR	-	0.0948	-	-	-	-	-	-	In vivo
Ptk2 (P34152-3)	Mus musculus	S843	DVRLSRGSIDREDGS	-	-	-	-	-	-	-	-	In vitro
SPR (P35270)	Homo sapiens	S213	QQLARETSVDPDMRK	0.339	0.5342	-	-	-	-	-	-	In vitro
HRH1 (P35367)	Homo sapiens	S396	FTWKRLRSHSRQYVS	0.321	0.0749	-	-	-	-	15107581	Non high throughput (15107581)	In vitro
HRH1 (P35367)	Homo sapiens	S398	WKRLRSHSRQYVSGL	0.94	0.1702	-	-	-	-	15107581	Non high throughput (15107581)	In vitro
OPRM1 (P35372)	Homo sapiens	S268	LKSVRMLSGSKEKDR	0.385	0.0948	-	-	-	-	-	-	In vivo
SNCA (P37840)	Homo sapiens	S129	NEAYEMPSEEGYQDY	0.253	0.8894	-	-	-	-	-	-	In vitro
GRIA1 (P42261)	Homo sapiens	S567	FSPYEWHSEEFEEGR	0.054	0.3249	-	-	-	-	-	-	In vitro
CDKN1B (P46527)	Homo sapiens	S10	NVRVSNGSPSLERMD	0.644	0.7505	-	-	-	-	-	-	In vitro
Rph3a (P47709)	Rattus norvegicus	S274	QGLRRANSVQASRPA	-	0.9725	-	-	-	-	-	-	In vitro
PLA2G4A (P47712)	Homo sapiens	S515	SDFATQDSFDDDELD	0.212	0.4409	-	-	-	-	11479288	Non high throughput (11479288)	-
VIM (P48616)	Bos taurus	S26	GTASRPSSTRSYVTT	-	0.7799	-	-	-	-	-	-	In vitro
VIM (P48616)	Bos taurus	S39	TTSTRTYSLGSALRP	-	0.4864	-	-	-	-	-	-	In vitro
VIM (P48616)	Bos taurus	S412	EGEESRISLPLPNFS	-	0.433	-	-	-	-	-	-	In vitro
VIM (P48616)	Bos taurus	S66	GVYATRSSAVRLRSG	-	0.5342	-	-	-	-	-	-	In vitro
VIM (P48616)	Bos taurus	S72	SSAVRLRSGVPGVRL	-	0.4476	-	-	-	-	-	-	In vitro
Gabrb1 (P50571)	Mus musculus	S409	IQYRKPLSSREGFGR	-	0.2817	-	-	-	-	8027073	Non high throughput (8027073)	-
Gabrb1 (P50571)	Mus musculus	S434	GRIRRRASQLKVKIP	-	0.4619	-	-	-	-	8027073	Non high throughput (8027073)	-
CLCN3 (P51790)	Homo sapiens	S109	ERHRRINSKKKESAW	0.128	0.494	-	-	-	-	14754994	Non high throughput (14754994)	In vitro
RRAD (P55042)	Homo sapiens	S273	AGTRRRESLGKKAKR	0.915	0.5017	-	-	-	-	-	-	In vitro
PLN (P61012)	Canis lupus familiaris	S16	RSAIRRASTIEMPQQ	-	0.0929	-	-	-	-	-	-	In vitro
Pln (P61014)	Mus musculus	S16	RSAIRRASTIEMPQQ	-	0.0909	-	-	-	-	2544595	Non high throughput (2544595)	-
Cdk5r1 (P61810)	Rattus norvegicus	S91	ENLKKSLSCANLSTF	-	0.3599	-	-	-	-	-	-	In vitro
Il6st (Q00560)	Mus musculus	S780	QVFSRSESTQPLLDS	-	0.6755	-	-	-	-	16036214	Non high throughput (16036214)	-
Mecp2 (Q00566)	Rattus norvegicus	S421	EKMPRAGSLESDGCP	-	0.8375	-	-	-	-	-	-	In vitro
HSF1 (Q00613)	Homo sapiens	S230	PKYSRQFSLEHVHGS	0.584	0.5139	-	-	-	-	11447121	Non high throughput (11447121)	In vitro
Grin2b (Q00960)	Rattus norvegicus	S1303	NKLRRQHSYDTFVDL	-	0.5758	-	-	-	-	-	-	In vitro
Cacna1c (Q01815)	Mus musculus	S1487	DYLTRDWSILGPHHL	-	0.0676	-	-	-	-	-	-	In vitro
Cacna1c (Q01815)	Mus musculus	S1545	VACKRLVSMNMPLNS	-	0.2715	-	-	-	-	-	-	In vitro
Cacna1b (Q02294)	Rattus norvegicus	S2126	SEKQRFYSCDRFGSR	-	0.7331	-	-	-	-	-	-	In vitro
Cacna1b (Q02294)	Rattus norvegicus	S784	RLQNLRASCEALYSE	-	0.4766	-	-	-	-	-	-	In vitro
Cacna1b (Q02294)	Rattus norvegicus	S896	ERARPRRSHSKEAPG	-	0.9657	-	-	-	-	-	-	In vitro
GFPT1 (Q06210)	Homo sapiens	S261	CNLSRVDSTTCLFPV	0.557	0.3215	-	-	-	-	-	-	In vitro
GRIN2B (Q13224)	Homo sapiens	S1303	NKLRRQHSYDTFVDL	0.872	0.5854	-	-	-	-	-	-	In vitro
ESPL1 (Q14674)	Homo sapiens	S1501	TDNWRKMSFEILRGS	0.927	0.5254	-	-	-	-	-	-	In vitro
SMAD2 (Q15796)	Homo sapiens	S110	SFSEQTRSLDGRLQV	0.488	0.3566	-	-	-	-	-	-	In vitro and in vivo
SMAD2 (Q15796)	Homo sapiens	S240	SDQQLNQSMDTGSPA	0.323	0.8313	-	-	-	-	-	-	In vitro and in vivo
SMAD2 (Q15796)	Homo sapiens	S260	TLSPVNHSLDLQPVT	0.145	0.5533	-	-	-	-	-	-	In vitro and in vivo
Dlg1 (Q62696)	Rattus norvegicus	S232	ITLERGNSGLGFSIA	-	0.3807	-	-	-	-	-	-	In vitro
Dlg1 (Q62696)	Rattus norvegicus	S39	SSIERVISIFQSNLF	-	0.1323	-	-	-	-	-	-	In vitro
Kcnd2 (Q63881)	Rattus norvegicus	S438	ARIRAAKSGSANAYM	-	0.3566	-	-	-	-	-	-	In vitro and in vivo
Kcnd2 (Q63881)	Rattus norvegicus	S459	LLSNQLQSSEDEPAF	-	0.4685	-	-	-	-	-	-	In vitro and in vivo
Tph2 (Q8CGV2)	Mus musculus	S19	YWARRGLSLDSAVPE	-	0.433	-	-	-	-	-	-	In vitro
RYR2 (Q92736)	Homo sapiens	S2808	YNRTRRISQTSQVSV	0.753	0.3529	-	-	-	-	14514795	Non high throughput (14514795)	In vitro
RYR2 (Q92736)	Homo sapiens	S2814	ISQTSQVSVDAAHGY	0.345	0.5017	-	-	-	-	-	-	In vivo
PPP1R14A (Q96A00)	Homo sapiens	S130	GLRQPSPSHDGSLSP	0.144	0.8828	-	-	-	-	12604330	Non high throughput (12604330)	In vitro
RCHY1 (Q96PM5)	Homo sapiens	S155	CLEDIHTSRVVAHVL	0.847	0.0107	-	-	-	-	-	-	In vitro and in vivo
CARD11 (Q9BXL7)	Homo sapiens	S116	KEPTRRFSTIVVEEG	0.795	0.4619	-	-	-	-	-	-	In vitro
Rims1 (Q9JIR4)	Rattus norvegicus	S241	RLQERSRSQTPLSTA	-	0.7459	-	-	-	-	-	-	In vitro
Rims1 (Q9JIR4)	Rattus norvegicus	S287	KQASRSRSEPPRERK	-	0.9606	-	-	-	-	-	-	In vitro
Pdc (Q9QW08)	Mus musculus	S54	KEILRQMSSPQSRDD	-	0.7951	-	-	-	-	-	-	In vitro
Lrp4 (Q9QYP1)	Rattus norvegicus	S1887	TTPERRGSLPDTGWK	-	0.7916	-	-	-	-	-	-	In vitro
Lrp4 (Q9QYP1)	Rattus norvegicus	S1900	WKHERKLSSESQV__	-	0.5854	-	-	-	-	-	-	In vitro
Gabbr1 (Q9WV18)	Mus musculus	S867	ITRGEWQSEAQDTMK	-	0.5176	-	-	-	-	-	-	In vitro
PEA15 (Q9Z297)	Cricetulus griseus	S116	KDIIRQPSEEEIIKL	-	0.4087	-	-	-	-	-	-	In vitro
FBXO43 (Q4G163)	Homo sapiens	T234	FSQQKTSTIDDSKDD	0.945	0.3872	-	-	-	-	-	-	In vitro
Brsk1 (B2DD29)	Rattus norvegicus	T189	VGDSLLETSCGSPHY	-	0.1759	-	-	-	-	-	-	In vitro and in vivo
SLN (O00631)	Homo sapiens	T5	___MGINTRELFLNF	0.223	0.0034	-	-	-	-	-	-	In vitro
ITGB1BP1 (O14713)	Homo sapiens	T38	GGLSRSSTVASLDTD	0.272	0.4901	-	-	-	-	-	-	In vivo
Trpv1 (O35433)	Rattus norvegicus	T704	WKLQRAITILDTEKS	-	0.0592	-	-	-	-	-	-	In vivo
ERBB2 (P04626)	Homo sapiens	T1172	ATLERPKTLSPGKNG	0.641	0.7982	-	-	-	-	8700533	Non high throughput (8700533)	-
ITGB1 (P05556)	Homo sapiens	T788	PIYKSAVTTVVNPKY	0.4	0.3087	-	-	-	-	-	-	In vivo
ITGB1 (P05556)	Homo sapiens	T789	IYKSAVTTVVNPKYE	0.67	0.2884	-	-	-	-	-	-	In vivo
Chrm4 (P08485)	Rattus norvegicus	T145	TYPARRTTKMAGLMI	-	-	-	-	-	-	-	-	In vitro and in vivo
Camk2a (P11275)	Rattus norvegicus	T305	KLKGAILTTMLATRN	-	0.2951	-	-	-	-	-	-	In vitro
Camk2a (P11275)	Rattus norvegicus	T306	LKGAILTTMLATRNF	-	0.3182	-	-	-	-	-	-	In vitro
Camk2a (P11275)	Rattus norvegicus	T310	ILTTMLATRNFSGGK	-	0.4017	-	-	-	-	-	-	In vitro
CALD1 (P12957)	Gallus gallus	T484	QNGERELTTPKLKST	-	0.853	-	-	-	-	-	-	In vitro
Myog (P12979)	Mus musculus	T87	VDRRRAATLREKRRL	-	0.4541	-	-	-	-	14751541	Non high throughput (14751541)	-
TNNT2 (P13789)	Bos taurus	T191	GYIQKAQTERKSGKR	-	0.662	-	-	-	-	-	-	In vitro
Gabrg2 (P22723)	Mus musculus	T395	DIRPRSATIQMNNAT	-	0.3087	-	-	-	-	8027073	Non high throughput (8027073)	-
ITPKA (P23677)	Homo sapiens	T311	EHAQRAVTKPRYMQW	0.826	0.5176	-	-	-	-	9155020	Non high throughput (9155020)	In vitro and in vivo
PLN (P26678)	Homo sapiens	T17	SAIRRASTIEMPQQA	0.522	0.1731	-	-	-	-	-	-	In vivo
Gjc1 (P28229)	Mus musculus	T337	HLPADLETLQREIRM	-	0.6089	-	-	-	-	-	-	In vitro
CHAT (P28329-3)	Homo sapiens	T456	VDNIRSATPEALAFV	-	-	-	-	-	-	-	-	In vitro
HRH1 (P35367)	Homo sapiens	T140	LRYLKYRTKTRASAT	0.825	0.0646	-	-	-	-	15107581	Non high throughput (15107581)	In vitro
HRH1 (P35367)	Homo sapiens	T142	YLKYRTKTRASATIL	0.164	0.0231	-	-	-	-	15107581	Non high throughput (15107581)	In vitro
PLN (P61012)	Canis lupus familiaris	T17	SAIRRASTIEMPQQA	-	0.1823	-	-	-	-	-	-	In vitro
Pln (P61014)	Mus musculus	T17	SAIRRASTIEMPQQA	-	0.1791	-	-	-	-	10988285, 2544595	Non high throughput (10988285, 2544595)	-
GLO1 (Q04760)	Homo sapiens	T107	ELTHNWGTEDDETQS	0.487	0.4831	-	-	-	-	-	-	In vivo
Myh9 (Q62812)	Rattus norvegicus	T1940	RRIVRKGTGDCSDEE	-	0.5254	-	-	-	-	-	-	In vivo
Sln (Q6SLE7)	Rattus norvegicus	T5	___MERSTQELFINF	-	0.0085	-	-	-	-	-	-	In vivo
RCHY1 (Q96PM5)	Homo sapiens	T154	ICLEDIHTSRVVAHV	0.837	0.0111	-	-	-	-	-	-	In vitro and in vivo
Sln (Q9CQD6)	Mus musculus	T5	___MERSTQELFINF	-	0.0085	-	-	-	-	-	-	In vitro
CAMK2A (Q9UQM7)	Homo sapiens	T286	SCMHRQETVDCLKKF	0.782	0.2817	-	-	-	-	16172120	Non high throughput (16172120)	In vitro and in vivo
CAMK2A (Q9UQM7)	Homo sapiens	T305	KLKGAILTTMLATRN	0.754	0.2918	-	-	-	-	-	-	In vitro
CAMK2A (Q9UQM7)	Homo sapiens	T306	LKGAILTTMLATRNF	0.607	0.3182	-	-	-	-	-	-	In vitro
N/A (Q9Z305)	Cavia porcellus	T1603	RTALRIKTEGNLEQA	-	0.346	-	-	-	-	-	-	In vitro
NCOR2 (Q9Y618)	Homo sapiens	S2426	ASGDRPPSVSSVHSE	0.177	-	-	-	-	-	-	-	in-vitro and in-vivo
NCOR2 (Q9Y618)	Homo sapiens	S2453	VWEDRPSSAGSTPFP	0.734	-	-	-	-	-	-	-	in-vitro
Itpr2 (P29995)	Rattus norvegicus	S150	EKNAMRVSLDAAGNE	-	0.2715	-	-	-	-	-	-	in-vitro
HDAC5 (Q9UQL6)	Homo sapiens	S259	FPLRKTASEPNLKVR	0.835	0.6806	-	-	-	-	-	-	in-vivo
Mcu (Q3UMR5)	Mus musculus	S91	VISVRLPSRRERCQF	-	0.1969	-	-	-	-	-	-	in-vivo
Mybpc3 (O70468)	Mus musculus	S302	SLLKKRDSFRRDSKL	-	0.391	-	-	-	-	-	-	in-vitro
TH (P07101-4)	Homo sapiens	S35	AIMVRGQSPRFIGRR	-	-	-	-	-	-	-	-	in-vitro
TH (P07101-4)	Homo sapiens	S44	RFIGRRQSLIEDARK	-	-	-	-	-	-	-	-	in-vitro
Kif3a (P28741)	Mus musculus	S698	KPETVIDSLLQ____	-	0.4901	-	-	-	-	-	-	in-vitro
Slc6a3 (P23977)	Rattus norvegicus	S13	CSVGPMSSVVAPAKE	-	0.3494	-	-	-	-	-	-	in-vitro
TCAP (O15273)	Homo sapiens	S157	GALRRSLSRSMSQEA	0.25	0.6906	-	-	-	-	-	-	in-vitro
STMN1 (P16949)	Homo sapiens	S16	KELEKRASGQAFELI	0.337	0.4149	-	-	-	-	-	-	in-vivo
Cpeb3 (Q7TN99)	Mus musculus	S298	SPLKKPFSSNVIAPP	-	0.5098	-	-	-	-	-	-	in-vivo
KIF3A (Q9Y496)	Homo sapiens	S687	KTGRRKRSAKPETVI	0.388	0.6712	-	-	-	-	-	-	in-vitro
Cpeb3 (Q7TN99)	Mus musculus	S420	GRRRGRSSLFPFEDA	-	0.2817	-	-	-	-	-	-	in-vitro and in-vivo
Ppp3ca (P63329)	Rattus norvegicus	S411	GKMARVFSVLREESE	-	0.2292	-	-	-	-	-	-	in-vivo
TH (P07101-4)	Homo sapiens	S19	KGFRRAVSELDAKQA	-	-	-	-	-	-	-	-	in-vitro
DAGLA (Q9Y4D2)	Homo sapiens	S782	APLATMESLSDTESL	0.651	0.4801	-	-	-	-	-	-	in-vitro
Abi1 (Q8CBW3)	Mus musculus	S88	SQLRRMESSINHISQ	-	0.4725	-	-	-	-	-	-	in-vivo
Mcu (Q3UMR5)	Mus musculus	S56	TAHQRPASWQSVGAA	-	0.3599	-	-	-	-	-	-	in-vivo
HDAC5 (Q9UQL6)	Homo sapiens	S498	RPLSRTQSSPLPQSP	0.94	0.9168	-	-	-	-	-	-	in-vivo
NOX5 (Q96PH1-4)	Homo sapiens	S475	WTNRLYESFKASDPL	-	-	-	-	-	-	-	-	in-vivo
SLC6A4 (P31645)	Homo sapiens	S13	LNSQKQLSACEDGED	0.186	0.6136	-	-	-	-	-	-	in-vitro
Syngap1 (Q9QUH6)	Rattus norvegicus	S1138	PSITKQHSQTPSTLN	-	0.8966	-	-	-	-	-	-	in-vivo
KCNQ2 (O43526-4)	Homo sapiens	S438	QTVRRSPSADQSLED	-	-	-	-	-	-	-	-	in-vitro
Neto2 (C6K2K4)	Rattus norvegicus	S409	SLREKEISADLADLS	-	0.2399	-	-	-	-	-	-	in-vitro and in-vivo
Cpeb3 (Q7TN99)	Mus musculus	S299	PLKKPFSSNVIAPPK	-	0.5055	-	-	-	-	-	-	in-vivo
CTNNB1 (P35222)	Homo sapiens	S552	QDTQRRTSMGGTQQQ	0.142	0.6755	-	-	-	-	-	-	in-vitro
BECN1 (Q14457)	Homo sapiens	S90	IPPARMMSTESANSF	0.467	0.4652	-	-	-	-	-	-	in-vitro and in-vivo
DLGAP1 (O14490-2)	Homo sapiens	S44	CRRMRSGSYIKAMGD	-	-	-	-	-	-	-	-	in-vivo
Wee2 (Q66JT0)	Mus musculus	S15	QGLNKKLSFSFCEED	-	0.6851	-	-	-	-	-	-	in-vitro and in-vivo
ID1 (P41134)	Homo sapiens	S36	GEVVRCLSEQSVAIS	0.692	0.1759	-	-	-	-	-	-	in-vitro
Fosb (P13346)	Mus musculus	S27	SAESQYLSSVDSFGS	-	0.6712	-	-	-	-	-	-	in-vivo
NR1H2 (P55055)	Homo sapiens	S426	RMLMKLVSLRTLSSV	0.159	0.1092	-	-	-	-	-	-	in-vivo
DAGLA (Q9Y4D2)	Homo sapiens	S808	RSIRGSPSLHAVLER	0.387	0.5665	-	-	-	-	-	-	in-vitro
Psmc5 (P62198)	Rattus norvegicus	S120	RVALRNDSYTLHKIL	-	0.3286	-	-	-	-	-	-	in-vivo
Cpeb3 (Q7TN99)	Mus musculus	S291	PSPLNPISPLKKPFS	-	0.5176	-	-	-	-	-	-	in-vivo
Cpeb3 (Q7TN99)	Mus musculus	S443	QALSSGLSSPTRCQN	-	0.6712	-	-	-	-	-	-	in-vivo
Cpeb3 (Q7TN99)	Mus musculus	S419	YGRRRGRSSLFPFED	-	0.2783	-	-	-	-	-	-	in-vitro and in-vivo
TCAP (O15273)	Homo sapiens	S161	RSLSRSMSQEAQRG_	0.844	0.5758	-	-	-	-	-	-	in-vitro
Oprm1 (P33535)	Rattus norvegicus	T370	STRVRQNTREHPSTA	-	0.708	-	-	-	-	-	-	in-vitro
KCNJ11 (Q14654)	Homo sapiens	T180	QAHRRAETLIFSKHA	0.891	0.0929	-	-	-	-	-	-	in-vivo
Fosb (P13346)	Mus musculus	T180	RNRRRELTDRLQAET	-	0.7369	-	-	-	-	-	-	in-vitro
Kif3a (P28741)	Mus musculus	T694	KRSAKPETVIDSLLQ	-	0.5533	-	-	-	-	-	-	in-vitro
Fosb (P13346)	Mus musculus	T149	PRRPREETLTPEEEE	-	0.9308	-	-	-	-	-	-	in-vitro
Grm1 (P23385)	Rattus norvegicus	T871	KLPCRSNTFLNIFRR	-	0.3053	-	-	-	-	-	-	in-vitro
SLC1A3 (P43003)	Homo sapiens	T26	QQGVRKRTLLAKKKV	0.297	0.2575	-	-	-	-	-	-	in-vitro
Trpc6 (Q61143)	Mus musculus	T487	RQLFRMKTSCFSWME	-	0.0174	-	-	-	-	-	-	in-vivo
SLC1A3 (P43003)	Homo sapiens	T37	KKKVQNITKEDVKSY	0.186	0.0734	-	-	-	-	-	-	in-vitro
Dpysl2 (O08553)	Mus musculus	T555	DNIPRRTTQRIVAPP	-	0.7629	-	-	-	-	-	-	in-vivo
Cpeb3 (Q7TN99)	Mus musculus	T446	SSGLSSPTRCQNGER	-	0.5992	-	-	-	-	-	-	in-vivo
CTNNB1 (P35222)	Homo sapiens	T472	ICALRHLTSRHQEAE	0.915	0.3774	-	-	-	-	-	-	in-vitro
CTNNB1 (P35222)	Homo sapiens	T332	VNIMRTYTYEKLLWT	0.009	0.0592	-	-	-	-	-	-	in-vitro
KCNJ11 (Q14654)	Homo sapiens	T224	MQVVRKTTSPEGEVV	0.299	0.3019	-	-	-	-	-	-	in-vivo
TNNT2 (P45379-2)	Homo sapiens	T203	GYIQKQAQTERKSGK	-	-	-	-	-	-	-	-	-
DLG1 (Q12959-8)	Homo sapiens	S116	RYQDEDTPPQEHISP	-	-	-	-	-	-	-	-	-
GABRG2 (P18507-2)	Homo sapiens	S382	NPAPTIDIRPRSATI	-	-	-	-	-	-	-	-	-
PDC (P20941-3)	Homo sapiens	S91	KEDENCLRKYRRQCM	-	-	-	-	-	-	-	-	-
CLCN3 (P51790-5)	Homo sapiens	S51	DNLLDGDTAVGTHYT	-	-	-	-	-	-	-	-	-
PTPRA (P18433-6)	Homo sapiens	S180	YMLRFKKYKQAGSHS	-	-	-	-	-	-	-	-	-
BCL10 (O95999)	Homo sapiens	S138	NNLSRSNSDESNFSE	0.846	0.6576	-	-	-	-	-	-	-
KRT18 (P05783)	Homo sapiens	S53	ISVSRSTSFRGGMGS	0.418	0.4541	-	-	-	-	-	-	-
MAPT (P10636-2)	Homo sapiens	S267	RVQSKIGSLDNITHV	-	-	-	-	-	-	-	-	-
MAPT (P10636-6)	Homo sapiens	S204	NVKSKIGSTENLKHQ	-	-	-	-	-	-	-	-	-
MAPT (P10636-6)	Homo sapiens	S298	RVQSKIGSLDNITHV	-	-	-	-	-	-	-	-	-
MAPT (P10636-8)	Homo sapiens	S356	RVQSKIGSLDNITHV	-	-	-	-	-	-	-	-	-
CREB1 (P16220)	Homo sapiens	S142	RKILNDLSSDAPGVP	-	0.5807	-	-	-	-	-	-	-
ATP2A2 (P16615-2)	Homo sapiens	S38	KLKERWGSNELPAEE	-	-	-	-	-	-	-	-	-
PTPRA (P18433)	Homo sapiens	S204	TEDVEPQSVPLLARS	0.557	0.7163	-	-	-	-	-	-	-
PDC (P20941-2)	Homo sapiens	S21	ERVSRKMSIQEYELI	-	-	-	-	-	-	-	-	-
DRD3 (P35462)	Homo sapiens	S229	RILTRQNSQCNSVRP	0.873	0.4409	-	-	-	-	-	-	-
GRIA1 (P42261)	Homo sapiens	S832	LIEFCYKSRSESKRM	0.458	0.1048	-	-	-	-	-	-	-
DLG1 (Q12959)	Homo sapiens	S232	ITLERGNSGLGFSIA	0.126	0.3599	-	-	-	-	-	-	-
IRF3 (Q14653)	Homo sapiens	S386	ARVGGASSLENTVDL	0.981	0.3215	-	-	-	-	-	-	-
ABI1 (Q8IZP0)	Homo sapiens	S88	SQLRRMESSINHISQ	0.782	0.4766	-	-	-	-	-	-	-
HOMER3 (Q9NSC5)	Homo sapiens	S120	ARLAREKSQDGGELT	0.386	0.6948	-	-	-	-	-	-	-
HOMER3 (Q9NSC5)	Homo sapiens	S159	EKLFRSQSADAPGPT	0.688	0.8741	-	-	-	-	-	-	-
HOMER3 (Q9NSC5)	Homo sapiens	S176	ERLKKMLSEGSVGEV	0.328	0.5419	-	-	-	-	-	-	-
RYR2 (H7BY35)	Homo sapiens	S2792	YNRTRRISQTSQVSV	-	0.3529	-	-	-	-	-	-	-
TRPV1 (Q8NER1)	Homo sapiens	S502	YFLQRRPSMKTLFVD	0.412	0.0105	-	-	-	-	-	-	-
SYN1 (P17600)	Homo sapiens	S605	AGPTRQASQAGPVPR	0.334	0.9909	-	-	-	-	-	-	-
NEFL (P07196)	Homo sapiens	S58	LSVRRSYSSSSGSLM	0.185	0.4017	-	-	-	-	-	-	-
NEFL (P07196)	Homo sapiens	S67	SSGSLMPSLENLDLS	0.173	0.3774	-	-	-	-	-	-	-
CACNA1S (Q13698)	Homo sapiens	S1575	PEICRTVSGDLAAEE	-	0.4766	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S244	KDRVKGKSDPYHATS	-	0.391	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S330	AGSTISNSHAQPFDF	-	0.708	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S364	AIVDQRPSSRASSRA	-	0.8013	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S365	IVDQRPSSRASSRAS	-	0.8162	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S369	RPSSRASSRASSRPR	-	0.9381	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S372	SRASSRASSRPRPDD	-	0.8828	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S373	RASSRASSRPRPDDL	-	0.8792	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S255	HATSGALSPAKDCGS	-	0.3321	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S296	VTGDRNNSSCRNYNK	-	0.4476	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S297	TGDRNNSSCRNYNKQ	-	0.5533	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S306	RNYNKQASEQNWANY	-	0.4409	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S314	EQNWANYSAEQNRMG	-	0.6375	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S325	NRMGQAGSTISNSHA	-	0.7369	-	-	-	-	-	-	-
N/A (Q53FJ6)	Homo sapiens	S328	GQAGSTISNSHAQPF	-	0.6906	-	-	-	-	-	-	-
MPZ (P25189)	Homo sapiens	S210	HKPGKDASKRGRQTP	0.909	0.5098	-	-	-	-	-	-	-
MPZ (P25189)	Homo sapiens	S233	SRSTKAVSEKKAKGL	0.397	0.494	-	-	-	-	-	-	-
CAMK2A (Q7LDD5)	Homo sapiens	S314	MLATRNFSGGKSGGN	-	0.5055	-	-	-	-	-	-	-
CALD1 (E7EX44)	Homo sapiens	S408	CFTPKGSSLKIEERA	-	0.422	-	-	-	-	-	-	-
CALD1 (E7EX44)	Homo sapiens	S441	AIVSKIDSRLEQYTS	-	0.5176	-	-	-	-	-	-	-
CALD1 (Q05682)	Homo sapiens	S73	VEVNAQNSVPDEEAK	0.782	0.8828	-	-	-	-	-	-	-
CALD1 (E7EX44)	Homo sapiens	S547	RNLWEKQSVDKVTSP	-	0.6806	-	-	-	-	-	-	-
N/A (A8K8W7)	Homo sapiens	S855	EPMRRSVSEAALAQP	-	0.7505	-	-	-	-	-	-	-
CREB1 (P16220)	Homo sapiens	S133	EILSRRPSYRKILND	-	0.5055	-	-	-	-	-	-	-
CACNA1C (Q13936)	Homo sapiens	S409	GVLSGEFSKEREKAK	0.737	0.2918	-	-	-	-	-	-	-
CACNA1C (F5H522)	Homo sapiens	S1512	DYLTRDWSILGPHHL	-	0.0676	-	-	-	-	-	-	-
CACNA1C (F5H522)	Homo sapiens	S1570	VACKRLVSMNMPLNS	-	0.2715	-	-	-	-	-	-	-
GRIA1 (P42261)	Homo sapiens	S645	LTVERMVSPIESAED	0.029	0.1323	-	-	-	-	-	-	-
GRIA1 (P42261)	Homo sapiens	S849	FCLIPQQSINEAIRT	0.238	0.1914	-	-	-	-	-	-	-
GRIA4 (P48058)	Homo sapiens	S862	IRNKARLSITGSVGE	0.708	0.3948	-	-	-	-	-	-	-
N/A (A8K0K0)	Homo sapiens	S849	FCLIPQQSINEAMRT	-	0.2436	-	-	-	-	-	-	-
GJC1 (P36383)	Homo sapiens	S326	AQEQQYGSHEENLPA	0.743	0.7036	-	-	-	-	-	-	-
GJC1 (P36383)	Homo sapiens	S381	SKAGSNKSTASSKSG	0.68	0.8013	-	-	-	-	-	-	-
GJC1 (P36383)	Homo sapiens	S384	GSNKSTASSKSGDGK	0.738	0.805	-	-	-	-	-	-	-
GJC1 (P36383)	Homo sapiens	S385	SNKSTASSKSGDGKT	0.824	0.712	-	-	-	-	-	-	-
GJC1 (P36383)	Homo sapiens	S387	KSTASSKSGDGKTSV	0.83	0.6531	-	-	-	-	-	-	-
GJC1 (P36383)	Homo sapiens	S393	KSGDGKTSVWI____	0.988	0.5211	-	-	-	-	-	-	-
MAPT (A0A0G2JS76)	Homo sapiens	S751	SNVSSTGSIDMVDSP	-	0.5665	-	-	-	-	-	-	-
NOS1 (C9J5P6)	Homo sapiens	S851	SYKVRFNSVSSYSDS	-	0.3529	-	-	-	-	-	-	-
VIM (P08670)	Homo sapiens	S39	TTSTRTYSLGSALRP	0.934	0.4725	-	-	-	-	-	-	-
DLG4 (P78352)	Homo sapiens	S73	ITLERGNSGLGFSIA	0.221	0.3704	-	-	-	-	-	-	-
OPRM1 (P35372)	Homo sapiens	S263	LMILRLKSVRMLSGS	0.189	0.0141	-	-	-	-	-	-	-
PTK2 (Q05397)	Homo sapiens	S843	DVRLSRGSIDREDGS	0.494	0.6948	-	-	-	-	-	-	-
RPH3A (Q9Y2J0)	Homo sapiens	S272	AGLRRANSVQASRPA	0.914	0.9664	-	-	-	-	-	-	-
VIM (P08670)	Homo sapiens	S26	GTASRPSSSRSYVTT	0.396	0.7629	-	-	-	-	-	-	-
VIM (P08670)	Homo sapiens	S412	EGEESRISLPLPNFS	0.035	0.4292	-	-	-	-	-	-	-
VIM (P08670)	Homo sapiens	S66	GVYATRSSAVRLRSS	0.166	0.5176	-	-	-	-	-	-	-
VIM (P08670)	Homo sapiens	S72	SSAVRLRSSVPGVRL	0.756	0.433	-	-	-	-	-	-	-
GABRB1 (P18505)	Homo sapiens	S409	IQYRKPLSSREAYGR	0.088	0.2436	-	-	-	-	-	-	-
GABRB1 (P18505)	Homo sapiens	S434	GRIRRRASQLKVKIP	0.418	0.4541	-	-	-	-	-	-	-
PLN (P26678)	Homo sapiens	S16	RSAIRRASTIEMPQQ	0.748	0.0888	-	-	-	-	-	-	-
CDK5R1 (Q8TAM4)	Homo sapiens	S91	ENLKKSLSCANLSTF	-	0.3704	-	-	-	-	-	-	-
IL6ST (P40189)	Homo sapiens	S782	QVFSRSESTQPLLDS	0.885	0.662	-	-	-	-	-	-	-
MECP2 (E9LUH4)	Homo sapiens	S423	EKMPRGGSLESDGCP	-	0.8421	-	-	-	-	-	-	-
CACNA1B (F6RH32)	Homo sapiens	S2130	SEKQRFYSCDRFGGR	-	0.7799	-	-	-	-	-	-	-
CACNA1B (F6RH32)	Homo sapiens	S784	RLQNLRASCEALYSE	-	0.4541	-	-	-	-	-	-	-
CACNA1B (F6RH32)	Homo sapiens	S892	ERPRPHRSHSKEAAG	-	0.9816	-	-	-	-	-	-	-
KCND2 (A4D0V9)	Homo sapiens	S438	ARIRAAKSGSANAYM	-	0.3529	-	-	-	-	-	-	-
KCND2 (A4D0V9)	Homo sapiens	S459	LLSNQLQSSEDEQAF	-	0.4441	-	-	-	-	-	-	-
TPH2 (Q8IWU9)	Homo sapiens	S19	YWARRGFSLDSAVPE	0.5	0.4186	-	-	-	-	-	-	-
RIMS1 (Q86UR5)	Homo sapiens	S218	RLQERSRSQTPLSTA	0.999	0.7799	-	-	-	-	-	-	-
RIMS1 (Q86UR5)	Homo sapiens	S265	QASSRSRSEPPRERK	0.867	0.9519	-	-	-	-	-	-	-
LRP4 (O75096)	Homo sapiens	S1887	ATPERRGSLPDTGWK	0.5	0.7505	-	-	-	-	-	-	-
LRP4 (O75096)	Homo sapiens	S1900	WKHERKLSSESQV__	0	0.562	-	-	-	-	-	-	-
N/A (A0A1U9X7R0)	Homo sapiens	S868	ITRGEWQSEAQDTMK	-	0.5211	-	-	-	-	-	-	-
PEA15 (Q15121)	Homo sapiens	S116	KDIIRQPSEEEIIKL	0.538	0.4087	-	-	-	-	-	-	-
N/A (A9CB80)	Homo sapiens	S1064	SCPIKEDSFLQRYSS	-	0.5139	-	-	-	-	-	-	-
N/A (A9CB80)	Homo sapiens	S1081	TGALTEDSIDDTFLP	-	0.725	-	-	-	-	-	-	-
N/A (A9CB80)	Homo sapiens	S1120	QPLNPAPSRDPHYQD	-	0.8681	-	-	-	-	-	-	-
GFAP (K7EMP8)	Homo sapiens	S13	ITSAARRSYVSSGEM	-	0.4369	-	-	-	-	-	-	-
GFAP (K7EMP8)	Homo sapiens	S17	ARRSYVSSGEMMVGG	-	0.4507	-	-	-	-	-	-	-
GFAP (K7EMP8)	Homo sapiens	S38	LGPGTRLSLARMPPP	-	0.6948	-	-	-	-	-	-	-
GFAP (K7EMP8)	Homo sapiens	S393	NLQIRETSLDTKSVS	-	0.5254	-	-	-	-	-	-	-
N/A (Q5U0M2)	Homo sapiens	S282	NSLQRVPSYDSFDSE	-	0.374	-	-	-	-	-	-	-
PDC (P20941)	Homo sapiens	S73	ERVSRKMSIQEYELI	0.49	0.4582	-	-	-	-	-	-	-
SYNGAP1 (A0A1U9X8L0)	Homo sapiens	S1073	PPLQRGKSQQLTVSA	-	0.9211	-	-	-	-	-	-	-
MCU (Q8NE86)	Homo sapiens	S92	VISVRLPSRRERCQF	0.936	0.1914	-	-	-	-	-	-	-
MYBPC3 (A8MXZ9)	Homo sapiens	S304	SLLKKSSSFRTPRDS	-	0.3704	-	-	-	-	-	-	-
KIF3A (E9PES4)	Homo sapiens	S723	KPETVIDSLLQ____	-	0.4901	-	-	-	-	-	-	-
SLC6A3 (Q01959)	Homo sapiens	S13	CSVGLMSSVVAPAKE	0.5	0.268	-	-	-	-	-	-	-
CPEB3 (Q5QP71)	Homo sapiens	S297	SPLKKPFSSNVIAPP	-	0.5055	-	-	-	-	-	-	-
CPEB3 (Q5QP71)	Homo sapiens	S388	MALNSRSSLFPFEDA	-	0.2064	-	-	-	-	-	-	-
PPP3CA (A0A0S2Z4C6)	Homo sapiens	S411	GKMARVFSVLREESE	-	0.2328	-	-	-	-	-	-	-
MCU (Q8NE86)	Homo sapiens	S57	TVHQRIASWQNLGAV	0.336	0.1643	-	-	-	-	-	-	-
SYNGAP1 (A0A1U9X8L0)	Homo sapiens	S1138	PSITKQHSQTPSTLN	-	0.8966	-	-	-	-	-	-	-
CPEB3 (Q5QP71)	Homo sapiens	S298	PLKKPFSSNVIAPPK	-	0.4979	-	-	-	-	-	-	-
FOSB (A0A024R0P6)	Homo sapiens	S27	SAESQYLSSVDSFGS	-	0.6806	-	-	-	-	-	-	-
N/A (A0A140VJS3)	Homo sapiens	S120	RVALRNDSYTLHKIL	-	0.3286	-	-	-	-	-	-	-
CPEB3 (Q5QP71)	Homo sapiens	S290	PSPLNPISPLKKPFS	-	0.5098	-	-	-	-	-	-	-
CPEB3 (Q5QP71)	Homo sapiens	S411	QALSSGLSSPTRCQN	-	0.6712	-	-	-	-	-	-	-
CPEB3 (Q5QP71)	Homo sapiens	S387	IMALNSRSSLFPFED	-	0.2002	-	-	-	-	-	-	-
ATP2A2 (P16615)	Homo sapiens	S38	KLKERWGSNELPAEE	0.07	0.422	-	-	-	-	-	-	-
CEBPB (P17676)	Homo sapiens	S325	EQLSRELSTLRNLFK	0.002	0.5382	-	-	-	-	-	-	-
CFL2 (Q9Y281)	Homo sapiens	S24	DMKVRKSSTQEEIKK	0.207	0.384	-	-	-	-	-	-	-
ADCY3 (O60266)	Homo sapiens	S1076	NVASRMESTGVMGNI	0.605	0.3392	-	-	-	-	-	-	-
QDPR (P09417)	Homo sapiens	S223	ITGKNRPSSGSLIQV	0.149	0.4149	-	-	-	-	-	-	-
GFAP (P14136)	Homo sapiens	S38	LGPGTRLSLARMPPP	0.368	0.6948	-	-	-	-	-	-	-
GFAP (P14136)	Homo sapiens	S13	ITSAARRSYVSSGEM	0.795	0.4369	-	-	-	-	-	-	-
GFAP (P14136)	Homo sapiens	S17	ARRSYVSSGEMMVGG	0.894	0.4507	-	-	-	-	-	-	-
KCND2 (Q9NZV8)	Homo sapiens	S438	ARIRAAKSGSANAYM	0.059	0.3529	-	-	-	-	-	-	-
TH (P07101)	Homo sapiens	S44	PGPSLTGSPWPGTAA	0.066	0.8279	-	-	-	-	-	-	-
SYN1 (P17600)	Homo sapiens	S568	PQATRQTSVSGPAPP	0.924	0.9903	-	-	-	-	-	-	-
ACACA (Q13085)	Homo sapiens	S25	RFIIGSVSEDNSEDE	0	0.4979	-	-	-	-	-	-	-
RYR1 (P21817)	Homo sapiens	S2843	KKKTRKISQSAQTYD	0.703	0.6948	-	-	-	-	-	-	-
GRIN2B (Q13224)	Homo sapiens	S383	VGKWKDKSLQMKYYV	0.724	0.1048	-	-	-	-	-	-	-
PPP1R9B (D3DTX6)	Homo sapiens	S116	ALLKLGTSVSERVSR	-	0.5254	-	-	-	-	-	-	-
PPP1R9B (D3DTX6)	Homo sapiens	S100	LSLPRASSLNENVDH	-	0.6227	-	-	-	-	-	-	-
MYLK (Q15746-7)	Homo sapiens	S838	LCGGGVGADGGGSDR	-	-	-	-	-	-	-	-	-
ITGB1BP1 (O14713-2)	Homo sapiens	T38	GGLSRSSTVASLDTD	-	-	-	-	-	-	-	-	-
CHAT (P28329)	Homo sapiens	T574	VDNIRSATPEALAFV	0.465	0.2034	-	-	-	-	-	-	-
BRSK1 (Q8TDC3)	Homo sapiens	T189	VGDSLLETSCGSPHY	0.685	0.1759	-	-	-	-	-	-	-
TRPV1 (Q8NER1)	Homo sapiens	T705	WKLQRAITILDTEKS	0.539	0.0581	-	-	-	-	-	-	-
CHRM4 (Q96RG8)	Homo sapiens	T146	TYPARRTTKMAGLMI	-	0.0581	-	-	-	-	-	-	-
CAMK2A (Q7LDD5)	Homo sapiens	T305	KLKGAILTTMLATRN	-	0.2918	-	-	-	-	-	-	-
CAMK2A (Q7LDD5)	Homo sapiens	T306	LKGAILTTMLATRNF	-	0.3182	-	-	-	-	-	-	-
CAMK2A (Q7LDD5)	Homo sapiens	T310	ILTTMLATRNFSGGK	-	0.3983	-	-	-	-	-	-	-
MYF4 (Q9HCA4)	Homo sapiens	T87	VDRRRAATLREKRRL	-	0.4507	-	-	-	-	-	-	-
SLN (A0A158RFT9)	Homo sapiens	T5	___MGINTRELFLNF	-	0.0034	-	-	-	-	-	-	-
nlgn1 (D2X2H5)	Homo sapiens	T759	CSPQRTTTNDLTHAQ	-	0.8623	-	-	-	-	-	-	-
CAMK2A (Q7LDD5)	Homo sapiens	T286	SCMHRQETVDCLKKF	-	0.2817	-	-	-	-	-	-	-
OPRM1 (P35372)	Homo sapiens	T372	STRIRQNTRDHPSTA	0.461	0.6806	-	-	-	-	-	-	-
FOSB (A0A024R0P6)	Homo sapiens	T180	RNRRRELTDRLQAET	-	0.7595	-	-	-	-	-	-	-
KIF3A (E9PES4)	Homo sapiens	T719	KRSAKPETVIDSLLQ	-	0.5533	-	-	-	-	-	-	-
FOSB (A0A024R0P6)	Homo sapiens	T149	PRRPREETLTPEEEE	-	0.9346	-	-	-	-	-	-	-
GRM1 (Q13255)	Homo sapiens	T871	KLPCRSNTFLNIFRR	-	0.2436	-	-	-	-	-	-	-
TRPC6 (Q9Y210)	Homo sapiens	T488	KQLFRMKTSCFSWME	0.457	0.0174	-	-	-	-	-	-	-
N/A (Q53ET2)	Homo sapiens	T555	DNIPRRTTQRIVAPP	-	0.7629	-	-	-	-	-	-	-
CPEB3 (Q5QP71)	Homo sapiens	T414	SSGLSSPTRCQNGER	-	0.5951	-	-	-	-	-	-	-
VPS72 (Q15906)	Homo sapiens	T86	RRKRRVVTKAYKEPL	0.905	0.6227	-	-	-	-	-	-	-
VPS72 (Q15906)	Homo sapiens	T137	RKSMRQSTAEHTRQT	0.99	0.7799	-	-	-	-	-	-	-
VPS72 (Q15906)	Homo sapiens	T168	PHCERPLTQEELLRE	0.927	0.6531	-	-	-	-	-	-	-
N/A (Q53H78)	Homo sapiens	T287	SMMYRQETVECLKKF	-	0.2715	-	-	-	-	-	-	-

Kinase

Substrate

Interactor

Interaction Network

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system TAS \| Reactome Pathway
R-HSA-168256	Immune System TAS \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins TAS \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling TAS \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa04012	ErbB signaling pathway
hsa04020	Calcium signaling pathway
hsa04114	Oocyte meiosis
hsa04310	Wnt signaling pathway
hsa04720	Long-term potentiation
hsa04722	Neurotrophin signaling pathway
hsa04725	Cholinergic synapse
hsa04740	Olfactory transduction
hsa04912	GnRH signaling pathway
hsa04916	Melanogenesis
hsa04971	Gastric acid secretion
hsa05152	Tuberculosis
hsa05214	Glioma

NCI Nature PID Pathways

Pathway ID	Pathway Name
fgf_pathway	FGF signaling pathway
ifngpathway	IFN-gamma pathway
pi3kplctrkpathway	Trk receptor signaling mediated by PI3K and PLC-gamma
tgfbrpathway	TGF-beta receptor signaling
wnt_calcium_pathway	Noncanonical Wnt signaling pathway