Graphics credits: COMPARTMENTS | More Info
| Parameter | Value |
|---|---|
| Gene | CACNA1B |
| Protein Name | F6RH32_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Voltage-dependent N-type calcium channel subunit alpha |
| Protein Family | Calcium channel alpha-1 subunit (TC 1.A.1.11) family |
| NCBI Gene ID | N/A |
| UniProt ID | F6RH32 |
| Enzyme Class | - |
| Molecular Weight | 262567 |
| Protein Length | 2340 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Membrane |
| Function (UniProt annotation) | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. |
| Gene Ontology | GO:0005245; GO:0005509; GO:0005891; GO:0034765 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK2A (Q9UQM7) | Homo sapiens | S2130 | SEKQRFYSCDRFGGR | N/A | 0.7799 | - | - | - | - | - | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S784 | RLQNLRASCEALYSE | N/A | 0.4541 | - | - | - | - | - | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S892 | ERPRPHRSHSKEAAG | N/A | 0.9816 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found