CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	SLN
Protein Name	SARCO_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Sarcolipin
Protein Family	Sarcolipin family
NCBI Gene ID	6588
UniProt ID	O00631
Enzyme Class	-
Molecular Weight	3762
Protein Length	31
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Sarcoplasmic reticulum membrane
Function (UniProt annotation)	Reversibly inhibits the activity of ATP2A1 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle-based, non-shivering thermogenesis (By similarity).
Gene Ontology	GO:0004857; GO:0006816; GO:0016021; GO:0016529; GO:0033017; GO:0043086; GO:0043242; GO:0051117; GO:0051924; GO:0070296; GO:0090281; GO:0120162; GO:1901020; GO:1901077; GO:1901877; GO:1901881; GO:1901894

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CAMK2A (Q9UQM7)	Homo sapiens	T5	___MGINTRELFLNF	0.223	0.0034	-	-	-	-	-	-	In vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found