| Gene |
Dpysl2
|
| Protein Name |
DPYL2_MOUSE |
| Organism |
Mus musculus (Mouse) |
| Alternative name(s) |
Dihydropyrimidinase-related protein 2 (DRP-2) (Unc-33-like phosphoprotein 2) (ULIP-2) |
| Protein Family |
Metallo-dependent hydrolases superfamily |
| NCBI Gene ID |
12934
|
| UniProt ID |
O08553
|
| Enzyme Class |
- |
| Molecular Weight |
62278 |
| Protein Length |
572 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm, cytosol |
| Function (UniProt annotation) |
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis. |
| Gene Ontology |
GO:0001975; GO:0005739; GO:0005829; GO:0005856; GO:0005886; GO:0006897; GO:0007010; GO:0007411; GO:0008017; GO:0010975; GO:0014049; GO:0016810; GO:0019901; GO:0021510; GO:0021772; GO:0030424; GO:0030425; GO:0030426; GO:0030516; GO:0032991; GO:0042220; GO:0042802; GO:0043005; GO:0043025; GO:0043195; GO:0043209; GO:0045664; GO:0048489; GO:0098793 |
