CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	PRPF3
Protein Name	PRPF3_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein)
Protein Family	N/A
NCBI Gene ID	9129
UniProt ID	O43395
Enzyme Class	-
Molecular Weight	77529
Protein Length	683
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus Nucleus speckle.
Function (UniProt annotation)	Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
Gene Ontology	GO:0000244; GO:0000375; GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005829; GO:0006397; GO:0008380; GO:0015030; GO:0016607; GO:0042802; GO:0046540; GO:0071005

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CHEK1 (O14757)	Homo sapiens	S161	EERKKQLSFISPPTP	0.266	0.7881	-	-	-	-	-	-	in-vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found