CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	STK17B
Protein Name	ST17B_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)
Protein Family	Protein kinase superfamily
NCBI Gene ID	9262
UniProt ID	O94768
Enzyme Class	2.7.11.1
Molecular Weight	42344
Protein Length	372
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	ATP + a protein = ADP + a phosphoprotein.
Localization	Nucleus
Function (UniProt annotation)	Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.
Gene Ontology	GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005793; GO:0005886; GO:0006468; GO:0006915; GO:0015629; GO:0035556; GO:0046777; GO:2000271

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
STK17B (O94768)	Homo sapiens	S10	RRRFDCRSISGLLTT	0.609	0.2988	-	-	-	-	-	-	-
STK17B (O94768)	Homo sapiens	S12	RFDCRSISGLLTTTP	0.362	0.2849	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found