CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	NEFL
Protein Name	NFL_BOVIN
Organism	Bos taurus (Bovine)
Alternative name(s)	Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Micro glutamic acid-rich protein) (Neurofilament triplet L protein)
Protein Family	Intermediate filament family
NCBI Gene ID	281348
UniProt ID	P02548
Enzyme Class	-
Molecular Weight	62646
Protein Length	555
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	N/A
Function (UniProt annotation)	Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
Gene Ontology	GO:0000226; GO:0005200; GO:0005882; GO:0005883; GO:0008022; GO:0008089; GO:0008090; GO:0014012; GO:0019896; GO:0030424; GO:0030674; GO:0031133; GO:0031594; GO:0033693; GO:0040011; GO:0042802; GO:0043209; GO:0043524; GO:0045109; GO:0045110; GO:0048812; GO:0050772; GO:0050885; GO:0060052; GO:0060074; GO:0098685; GO:0098981; GO:0099160; GO:0099182; GO:0099184; GO:1904115

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CAMK2A (Q9UQM7)	Homo sapiens	S58	LSVRRSYSSSSGSLM	N/A	0.3983	-	-	-	-	-	-	In vitro
CAMK2A (Q9UQM7)	Homo sapiens	S67	SSGSLMPSLESLDLS	N/A	0.3566	-	-	-	-	-	-	In vitro
CAMK2A (Q9UQM7)	Homo sapiens	S70	SLMPSLESLDLSQVA	N/A	0.3286	-	-	-	-	-	-	In vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
bta05014	Amyotrophic lateral sclerosis (ALS)

No NCI Nature pathways found