| Gene |
Th
|
| Protein Name |
TY3H_RAT |
| Organism |
Rattus norvegicus (Rat) |
| Alternative name(s) |
Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH) |
| Protein Family |
Biopterin-dependent aromatic amino acid hydroxylase family |
| NCBI Gene ID |
25085
|
| UniProt ID |
P04177
|
| Enzyme Class |
1.14.16.2 |
| Molecular Weight |
55966 |
| Protein Length |
498 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
L-tyrosine + tetrahydrobiopterin + O(2) = L-dopa + 4a-hydroxytetrahydrobiopterin. |
| Localization |
N/A |
| Function (UniProt annotation) |
Plays an important role in the physiology of adrenergic neurons. |
| Gene Ontology |
GO:0001666; GO:0001963; GO:0001975; GO:0004497; GO:0004511; GO:0005634; GO:0005737; GO:0005739; GO:0005790; GO:0005829; GO:0006585; GO:0006631; GO:0006665; GO:0007507; GO:0007601; GO:0007605; GO:0007612; GO:0007613; GO:0007617; GO:0007626; GO:0008016; GO:0008021; GO:0008198; GO:0008199; GO:0009414; GO:0009416; GO:0009635; GO:0009651; GO:0009898; GO:0010038; GO:0010043; GO:0010259; GO:0014070; GO:0014823; GO:0015842; GO:0016137; GO:0016597; GO:0017085; GO:0018963; GO:0019825; GO:0019899; GO:0019904; GO:0021987; GO:0030424; GO:0030425; GO:0030659; GO:0031667; GO:0032355; GO:0032496; GO:0033076; GO:0033162; GO:0034617; GO:0035094; GO:0035176; GO:0035240; GO:0035690; GO:0035900; GO:0035902; GO:0042136; GO:0042214; GO:0042418; GO:0042421; GO:0042423; GO:0042462; GO:0042493; GO:0042745; GO:0042755; GO:0043005; GO:0043025; GO:0043195; GO:0043204; GO:0043434; GO:0045471; GO:0045472; GO:0046684; GO:0048545; GO:0048596; GO:0050890; GO:0051289; GO:0051412; GO:0051602; GO:0052314; GO:0070848; GO:0071287; GO:0071312; GO:0071316; GO:0071333; GO:0071363 |
