| Gene |
HMGN1
|
| Protein Name |
HMGN1_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Non-histone chromosomal protein HMG-14 (High mobility group nucleosome-binding domain-containing protein 1) |
| Protein Family |
HMGN family |
| NCBI Gene ID |
3150
|
| UniProt ID |
P05114
|
| Enzyme Class |
- |
| Molecular Weight |
10659 |
| Protein Length |
100 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus. |
| Function (UniProt annotation) |
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity). |
| Gene Ontology |
GO:0000720; GO:0000785; GO:0003677; GO:0005634; GO:0005654; GO:0005737; GO:0006283; GO:0006325; GO:0006357; GO:0010224; GO:0010225; GO:0031492; GO:0032786; GO:0040034; GO:0048597; GO:0050678; GO:1901666 |
