| Gene |
NEFL
|
| Protein Name |
NFL_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein) |
| Protein Family |
Intermediate filament family |
| NCBI Gene ID |
4747
|
| UniProt ID |
P07196
|
| Enzyme Class |
- |
| Molecular Weight |
61517 |
| Protein Length |
543 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
N/A |
| Function (UniProt annotation) |
Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. |
| Gene Ontology |
GO:0000165; GO:0000226; GO:0005088; GO:0005200; GO:0005737; GO:0005829; GO:0005883; GO:0008022; GO:0008089; GO:0008090; GO:0014012; GO:0019896; GO:0019904; GO:0021510; GO:0021766; GO:0021987; GO:0030424; GO:0030426; GO:0030674; GO:0031133; GO:0031594; GO:0033693; GO:0040011; GO:0042802; GO:0043209; GO:0043274; GO:0043434; GO:0043524; GO:0045105; GO:0045109; GO:0046982; GO:0048812; GO:0050772; GO:0050885; GO:0051258; GO:0051412; GO:0060052; GO:0060074; GO:0098685; GO:0098981; GO:0099160; GO:0099182; GO:0099184; GO:1903935; GO:1903937; GO:1904115 |
