CaMKinet | Result

Graphics credits: COMPARTMENTS | More Info

Sequence Viewer

Parameter	Value
Gene	ADRB2
Protein Name	ADRB2_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)
Protein Family	G-protein coupled receptor 1 family
NCBI Gene ID	154
UniProt ID	P07550
Enzyme Class	-
Molecular Weight	46459
Protein Length	413
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cell membrane
Function (UniProt annotation)	Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Gene Ontology	GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004935; GO:0004941; GO:0005634; GO:0005764; GO:0005768; GO:0005769; GO:0005886; GO:0005887; GO:0006898; GO:0007166; GO:0007171; GO:0007186; GO:0007188; GO:0007190; GO:0008179; GO:0008333; GO:0009409; GO:0010008; GO:0010739; GO:0015459; GO:0016020; GO:0016324; GO:0016579; GO:0030501; GO:0030665; GO:0031398; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051379; GO:0051380; GO:0061024; GO:0061885; GO:0071875; GO:0071880; GO:0071902; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:1990911; GO:2000481; GO:2000969

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MKNK2 (Q9HBH9)	Homo sapiens	S355	KAYGNGYSSNGNTGE	0.53	0.4652	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S356	AYGNGYSSNGNTGEQ	0.173	0.384	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S411	RNCSTNDSLL_____	0.56	0.3948	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S364	NGNTGEQSGYHVEQE	0.174	0.5951	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S401	VPSDNIDSQGRNCST	0.543	0.6136	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S407	DSQGRNCSTNDSLL_	0.721	0.4256	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	T384	LCEDLPGTEDFVGHQ	0.302	0.2328	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	T408	SQGRNCSTNDSLL__	0.612	0.3872	-	-	-	-	-	-	-

Interaction Network

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found