| Parameter | Value |
|---|---|
| Gene | Gap43 |
| Protein Name | NEUM_RAT |
| Organism | Rattus norvegicus (Rat) |
| Alternative name(s) | Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Protein F1) |
| Protein Family | Neuromodulin family |
| NCBI Gene ID | 29423 |
| UniProt ID | P07936 |
| Enzyme Class | - |
| Molecular Weight | 23603 |
| Protein Length | 226 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell projection, filopodium membrane Note=Cytoplasmic surface of growth cone and synaptic plasma membranes. |
| Function (UniProt annotation) | This protein is associated with nerve growth. It is a major component of the motile growth cones that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction (By similarity). |
| Gene Ontology | GO:0001786; GO:0005516; GO:0005737; GO:0007399; GO:0010001; GO:0014069; GO:0016198; GO:0030054; GO:0030426; GO:0031527; GO:0032584; GO:0035727; GO:0040008; GO:0042246; GO:0045165; GO:0051489; GO:0098982; GO:0099150; GO:1901981 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PHKG1* (P00518) | Oryctolagus cuniculus | S41 | AATKIQASFRGHITR | N/A | 0.6712 | TP | certain | experimental | 132 | 72 | 135 | 16 | | 8454596 | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found